Gotlib V Ia, Taponaĭnen N Ia, Pelevina I I
Tsitologiia. 1985 May;27(5):607-10.
A possibility to detect the low level residual DNA damages was undertaken in HeLa cells during a long time after irradiation. The mixture of two inhibitors of replicative and reparative syntheses (hydroxyurea and beta-arabinosylcytosine) was added to the HeLa monolayer culture cells 6--24 hours after irradiation, when the potentially lethal damages was removed. A decrease in cell survival was shown. These data suggest that a certain amount of damages may still remain in DNA of irradiated cells.
在照射后的很长一段时间内，对HeLa细胞中低水平残留DNA损伤的检测成为可能。在照射后6至24小时，当潜在致死性损伤被消除时，将两种复制和修复合成抑制剂（羟基脲和β-阿拉伯糖胞苷）的混合物添加到HeLa单层培养细胞中。结果显示细胞存活率下降。这些数据表明，受照射细胞的DNA中可能仍残留一定量的损伤。
