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病例报告:通过非接触式宫腔镜技术诊断的宫颈癌放化疗后的脂肪干细胞。

Case Report: SVF after chemoradiotherapy for cervical cancer diagnosed by non-contact hysteroscopic technique.

作者信息

Sun Xuemei, He Yinghua, Yang Xuedong, Wu Yu, Yang Yanhuan, Wang Yanping, Fan Xiuhua

机构信息

Changchun University of Chinese Medicine, Changchun, Jilin, China.

Department of Proctology, Guang'anmen Hospital, China Academy of Traditional Chinese Medicine, Beijing, China.

出版信息

Front Med (Lausanne). 2025 Mar 10;12:1511052. doi: 10.3389/fmed.2025.1511052. eCollection 2025.

DOI:10.3389/fmed.2025.1511052
PMID:40130246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11930810/
Abstract

Sigmoidovaginal fistula (SVF) is an extremely distressing and complex condition that significantly impacts a patient's quality of life. The successful management of SVF relies on accurately identifying the fistula's location and tract. However, preoperative localization can be challenging in certain cases. In this report, we describe a rare complication in a patient with stage IVA cervical cancer who developed SVF after concurrent chemoradiotherapy. Conventional diagnostic methods, including electron colonoscopy, methylene blue testing, and fistulography, were unable to locate the fistula. As an alternative, we used a non-contact hysteroscopic technique, which successfully identified the location, size, and number of fistulas. This method is particularly effective for patients with SVF, especially in postmenopausal women with narrowed or adherent vaginal tracts, women with intact hymen, and those with complex, high-grade vaginal fistulas resulting from cancer treatment with chemoradiotherapy.

摘要

乙状结肠阴道瘘(SVF)是一种极其痛苦且复杂的病症,会严重影响患者的生活质量。SVF的成功治疗依赖于准确识别瘘管的位置和通道。然而,在某些情况下,术前定位可能具有挑战性。在本报告中,我们描述了一名IV A期宫颈癌患者在同步放化疗后发生SVF的罕见并发症。包括电子结肠镜检查、亚甲蓝试验和瘘管造影在内的传统诊断方法均无法确定瘘管位置。作为一种替代方法,我们使用了非接触式宫腔镜技术,该技术成功识别了瘘管的位置、大小和数量。这种方法对SVF患者特别有效,尤其是绝经后阴道狭窄或粘连的女性、处女膜完整的女性,以及因放化疗癌症治疗导致复杂、高级别阴道瘘的患者。

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本文引用的文献

1
Colovaginal Fistula: An Uncommon Complication After Vaginal Hysterectomy and Pelvic Floor Repair With Mesh Surgery.结肠阴道瘘:阴道子宫切除及盆底网状物修补术后的罕见并发症
Cureus. 2023 Dec 28;15(12):e51221. doi: 10.7759/cureus.51221. eCollection 2023 Dec.
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Rectovaginal fistula repair by Martius flap after exclusive chemoradiation in a patient with advanced cervical cancer.
Int J Gynecol Cancer. 2023 Sep 4;33(9):1473-1474. doi: 10.1136/ijgc-2023-004365.
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[Chinese experts consensus on diagnosis and treatment of rectovaginal fistula (2022 edition)].《直肠阴道瘘诊断与治疗中国专家共识(2022年版)》
Zhonghua Wei Chang Wai Ke Za Zhi. 2022 Dec 25;25(12):1073-1080. doi: 10.3760/cma.j.cn441530-20220823-00355.
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Closure of recurrent colovaginal fistulas using AMPLATZER occluder device.使用 AMPLATZER 封堵器封闭复发性结肠阴道瘘。
BMJ Open Gastroenterol. 2022 Jun;9(1). doi: 10.1136/bmjgast-2022-000921.
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Application of 'no-touch' hysteroscopy (vaginoscopy) for the treatment of abnormal uterine bleeding in adolescence.“非接触式”宫腔镜检查(阴道镜检查)在青春期异常子宫出血治疗中的应用。
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Colorectal Dis. 2016 May;18(5):483-7. doi: 10.1111/codi.13118.
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Int J Colorectal Dis. 2013 Apr;28(4):591. doi: 10.1007/s00384-012-1503-x. Epub 2012 Jun 2.
10
Colovaginal and colovesical fistulae: the diagnostic paradigm.阴道结肠和结肠膀胱瘘:诊断模式。
Tech Coloproctol. 2012 Apr;16(2):119-26. doi: 10.1007/s10151-012-0807-8. Epub 2012 Feb 14.