Samra Sahej, Attarian Hrayr, Malkani Roneil
University of Southern California, Los Angeles, California.
Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
J Clin Sleep Med. 2025 Jul 1;21(7):1311-1313. doi: 10.5664/jcsm.11704.
Current treatments for rapid eye movement sleep behavior disorder are not always effective and can lead to dose-limited adverse events, and new treatments are needed for this condition. We present a case of a patient with treatment-refractory isolated rapid eye movement sleep behavior disorder who had a dramatic and sustained improvement in dream enactment behaviors using oral tinctures containing cannabidiol and tetrahydrocannabinol without adverse events over 5 years of follow-up.
Samra S, Attarian H, Malkani R. The use of cannabinoid therapy in treatment-refractory isolated REM sleep behavior disorder: a case report. . 2025;21(7):1311-1313.
快速眼动睡眠行为障碍的现有治疗方法并不总是有效,且可能导致剂量受限的不良事件,因此需要针对这种情况的新治疗方法。我们报告一例难治性孤立性快速眼动睡眠行为障碍患者,该患者使用含大麻二酚和四氢大麻酚的口服酊剂后,梦呓行为得到显著且持续改善,在5年随访期间无不良事件。
Samra S, Attarian H, Malkani R. 大麻素疗法在难治性孤立性快速眼动睡眠行为障碍治疗中的应用:一例报告。. 2025;21(7):1311 - 1313.