Alagbe Oludare Oladayo, Iliya Rahamatu Shamsiyyah, Rotimi Bosede, Solomon Amos
Accident and Emergency, Federal Medical Centre, Bida, Niger, Nigeria
Public Health, Ahmadu Bello University Distance Learning Centre, Zaria, Kaduna, Nigeria.
BMJ Open. 2025 Mar 25;15(3):e091739. doi: 10.1136/bmjopen-2024-091739.
This study aimed to assess mothers' awareness, perceptions and willingness to accept malaria vaccines for their children under 5 years old in a city in Northcentral Nigeria.
The research employed a hospital-based cross-sectional observational study design to gather and analyse relevant data.
The study was conducted at the immunisation clinic of a tertiary health centre in Northcentral Nigeria.
A total of 376 women of reproductive age (15-49 years) participated in the study. All participants resided in the study area and had children aged 0-5 years.
The study evaluated mothers' awareness of the malaria vaccine, their perceptions about its use and their willingness to vaccinate their children under 5 years of age.
Awareness of the malaria vaccine was low, with only 89 mothers (23.7%) reporting prior knowledge of it. Despite this, an overwhelming 366 participants (97.3%) expressed willingness to vaccinate their children and 352 (93.6%) were willing to pay for the vaccine. Concerns about injection site reactions, fever and pain were common, with 126 mothers (33.6%) preferring an oral vaccine. Positive perception significantly influenced willingness to vaccinate (χ²=5.987, p=0.014). Additionally, age, marital status, educational level and income were significantly associated with willingness to vaccinate (p=0.002, 0.025, 0.015, 0.026, respectively). At the multivariate level, younger maternal age (OR=1.179, p=0.011) and higher income (OR=1.040, p=0.049) emerged as direct predictors of vaccine acceptance.
While awareness of malaria vaccines among mothers was limited, there was a strong willingness to vaccinate, influenced by positive perceptions, younger maternal age and higher income. The findings highlight the importance of targeted educational campaigns to improve awareness and acceptance of malaria vaccines. Future studies should explore interventions to enhance vaccine acceptance and address potential barriers to vaccine awareness.
本研究旨在评估尼日利亚中北部某城市5岁以下儿童母亲对疟疾疫苗的知晓情况、认知程度以及为其子女接种疟疾疫苗的意愿。
本研究采用基于医院的横断面观察性研究设计来收集和分析相关数据。
该研究在尼日利亚中北部一家三级医疗中心的免疫诊所进行。
共有376名育龄妇女（15 - 49岁）参与了本研究。所有参与者均居住在研究区域内，且育有0 - 5岁的子女。
本研究评估了母亲们对疟疾疫苗的知晓情况、对其使用的认知以及为5岁以下子女接种疫苗的意愿。
母亲们对疟疾疫苗的知晓率较低，只有89名母亲（23.7%）报告之前了解过该疫苗。尽管如此，绝大多数366名参与者（97.3%）表示愿意为其子女接种疫苗，352名（93.6%）愿意为疫苗付费。对注射部位反应、发热和疼痛的担忧较为常见，126名母亲（33.6%）更倾向于口服疫苗。积极的认知显著影响了接种意愿（χ² = 5.987，p = 0.014）。此外，年龄、婚姻状况、教育水平和收入与接种意愿显著相关（分别为p = 0.002、0.025、0.015、0.026）。在多变量层面，母亲年龄较小（OR = 1.179，p = 0.011）和收入较高（OR = 1.040，p = 0.049）成为疫苗接受度的直接预测因素。
虽然母亲们对疟疾疫苗的知晓有限，但受积极认知、母亲年龄较小和收入较高的影响，表示愿意接种疫苗的意愿强烈。研究结果凸显了开展针对性教育活动以提高对疟疾疫苗的知晓率和接受度的重要性。未来研究应探索增强疫苗接受度的干预措施，并解决疫苗知晓方面的潜在障碍。
