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光声成像在运动医学中有何作用:当前的证据

Is There a Role of Photoacoustic Imaging in Sports Medicine: Evidence Today.

作者信息

Ma Chenggong, Chadha Angat Naresh, Wu Cheng, Giannoudis Peter V, Guo Jiong Jiong

机构信息

Department of Orthopedics and Sports Medicine, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.

School of Rail Transportation, Soochow University, Suzhou, People's Republic of China.

出版信息

Orthop Surg. 2025 Jun;17(6):1589-1603. doi: 10.1111/os.70031. Epub 2025 Mar 25.

DOI:10.1111/os.70031
PMID:40132986
Abstract

Diagnostic imaging in sports medicine includes traditional imaging modalities such as x-ray, computed tomography (CT), and magnetic resonance imaging (MRI). Despite having certain advantages, these imaging techniques often have lower sensitivity and specificity, making it difficult to detect soft tissue injuries and early-stage cartilage damage. They also lack the ability to assess the biomechanical properties and functional states of tissues. Photoacoustic imaging (PAI) offers a powerful, non-ionizing, and cost-effective alternative to traditional imaging techniques in the diagnosis and therapeutic monitoring of sports injuries. PAI combines the benefits of optical imaging and ultrasound to provide high-resolution images of deep tissues, including tendons and ligaments. This technology uses pulsed lasers to irradiate tissues, causing thermal expansion and generating ultrasound waves, which are then captured and converted into images. PAI is particularly adept at depicting blood vessels and soft tissues with high resolution and sensitivity to the optical absorption contrasts of oxy- and deoxyhemoglobin. It can assess tissue oxygenation and metabolic activities, which are crucial for evaluating the healing process in sports injuries. Herein, the role of PAI in sports medicine is assessed and particularly its advantages over traditional imaging methods such as x-rays, CT scans, and MRI scans in diagnosing musculoskeletal injuries.

摘要

运动医学中的诊断成像包括传统成像方式,如X射线、计算机断层扫描(CT)和磁共振成像(MRI)。尽管这些成像技术具有一定优势,但它们的敏感性和特异性往往较低,难以检测软组织损伤和早期软骨损伤。它们还缺乏评估组织生物力学特性和功能状态的能力。光声成像(PAI)在运动损伤的诊断和治疗监测方面为传统成像技术提供了一种强大、非电离且经济高效的替代方法。PAI结合了光学成像和超声的优点,能够提供包括肌腱和韧带在内的深部组织的高分辨率图像。该技术使用脉冲激光照射组织,引起热膨胀并产生超声波,然后将其捕获并转换为图像。PAI特别擅长以高分辨率描绘血管和软组织,并对氧合血红蛋白和脱氧血红蛋白的光吸收对比度敏感。它可以评估组织氧合和代谢活动,这对于评估运动损伤的愈合过程至关重要。在此,评估了PAI在运动医学中的作用,特别是其在诊断肌肉骨骼损伤方面相对于传统成像方法(如X射线、CT扫描和MRI扫描)的优势。

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