Guo Ya-Xiong, Yan Xiong, Liu Xu-Chang, Liu Yu-Xiang, Liu Chun
Surgical Unit 1, Shanxi Combined Traditional Chinese and Western Medicine Hospital, Taiyuan 030072, Shanxi Province, China.
No. 1 Clinical Medical School, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
World J Nephrol. 2025 Mar 25;14(1):100825. doi: 10.5527/wjn.v14.i1.100825.
In this editorial, we discuss the article by Singh published in , stating the need for timely adjustments in inflammatory bowel disease (IBD) patients' long-term management plans. IBD is chronic and lifelong, with recurrence and remission cycles, including ulcerative colitis and Crohn's disease. It's exact etiology is unknown but likely multifactorial. Related to gut flora and immune issues. Besides intestinal symptoms, IBD can also affect various extraintestinal manifestations such as those involving the skin, joints, eyes and urinary system. The anatomical proximity of urinary system waste disposal to that of the alimentary canal makes early detection and the differentiation of such symptoms very difficult. Various studies show that IBD and it's first-line drugs have nephrotoxicity, impacting the patients' life quality. Existing guidelines give very few references for kidney lesion monitoring. Singh 's plan aims to improve treatment management for IBD patients with glomerular filtration rate decline, specifically those at risk. Most of IBD patients are young and they need lifelong therapy. So early therapy cessation, taking into account drug side effects, can be helpful. Artificial intelligence-driven diagnosis and treatment has a big potential for management improvements in IBD and other chronic diseases.
在这篇社论中,我们讨论了辛格发表的文章,文中指出炎症性肠病(IBD)患者长期管理计划需要及时调整。IBD是一种慢性终身疾病,有复发和缓解周期,包括溃疡性结肠炎和克罗恩病。其确切病因不明,但可能是多因素的,与肠道菌群和免疫问题有关。除肠道症状外,IBD还可影响各种肠外表现,如涉及皮肤、关节、眼睛和泌尿系统的表现。泌尿系统废物处理与消化道在解剖位置上相近,使得此类症状的早期检测和鉴别非常困难。各种研究表明,IBD及其一线药物具有肾毒性,影响患者生活质量。现有指南对肾脏病变监测的参考很少。辛格的计划旨在改善肾小球滤过率下降的IBD患者,特别是有风险的患者的治疗管理。大多数IBD患者很年轻,他们需要终身治疗。因此,考虑到药物副作用而尽早停止治疗可能会有所帮助。人工智能驱动的诊断和治疗在改善IBD和其他慢性病的管理方面具有很大潜力。