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体力活动在炎症性肠病中的作用:未解之谜是什么?接下来该怎么做?

Unresolved conundrum of the role of physical activity in inflammatory bowel disease: What next?

机构信息

Department of Surgery, Sri Balaji Vidyapeeth, Pondicherry 607402, India.

出版信息

World J Gastroenterol. 2024 Jun 7;30(21):2744-2747. doi: 10.3748/wjg.v30.i21.2744.

DOI:10.3748/wjg.v30.i21.2744
PMID:38899327
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11185299/
Abstract

There is considerable controversy on the role of physical activity in irritable bowel disease (IBD) since published reports are conflicting. It is well known that there is known relapse with specific treatment in IBD. This, in addition to onset of extraintestinal symptoms creates a need to think of alternate approaches. In this context, the current article describes the need of a multi-institutional study with standard protocol of physical activity for documenting its effect on both the primary disease and the extra alimentary manifestations. This paper also points out the possibility of using adjuvant complementary medicine such as yoga, whose effects have been documented in other diseases like irritable bowel syndrome. A third approach could be to focus on the intestinal dysbiosis in IBD and concentrate on research on restoring the microbial flora to normal, to see whether the extra-intestinal symptoms are alleviated.

摘要

关于体力活动在肠易激综合征(IBD)中的作用存在相当大的争议,因为已发表的报告相互矛盾。众所周知,IBD 采用特定治疗后会有已知的复发。除了肠道外症状的发作之外,这需要考虑其他方法。在这种情况下,本文描述了进行多机构研究的必要性,该研究采用标准的体力活动方案来记录其对原发性疾病和肠道外表现的影响。本文还指出了使用辅助性补充药物(如瑜伽)的可能性,瑜伽的作用已在其他疾病(如肠易激综合征)中得到证实。第三种方法可能是专注于 IBD 的肠道菌群失调,并集中研究恢复微生物菌群正常,以观察肠道外症状是否得到缓解。

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本文引用的文献

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Yoga Therapy in Functional Dyspepsia. A Narrative Review.瑜伽治疗功能性消化不良。一种叙述性综述。
J Gastrointestin Liver Dis. 2023 Dec 22;32(4):513-525. doi: 10.15403/jgld-4867.
2
A systematic review of the effect of structured exercise on inflammation and body composition in inflammatory bowel disease.系统评价结构性运动对炎症性肠病炎症和身体成分的影响。
Int J Colorectal Dis. 2023 May 25;38(1):143. doi: 10.1007/s00384-023-04437-2.
3
Approach to Treatment Failure in Inflammatory Bowel Disease.炎症性肠病治疗失败的处理方法
Gastroenterol Hepatol (N Y). 2022 Jun;18(6):360-363.
4
Physical Activity in Patients With Inflammatory Bowel Disease: A Narrative Review.炎症性肠病患者的身体活动:一篇叙述性综述。
Inflamm Bowel Dis. 2022 Jul 1;28(7):1100-1111. doi: 10.1093/ibd/izab218.
5
An integrative review of physical activity in adults with inflammatory bowel disease.对炎症性肠病成年患者身体活动情况的综合综述。
Intest Res. 2022 Jan;20(1):43-52. doi: 10.5217/ir.2020.00049. Epub 2021 Jan 22.
6
Correction to Lancet Gastroenterol Hepatol 2020; 5: 908-17.《柳叶刀·胃肠病与肝脏病学》2020年第5卷第908 - 17页勘误
Lancet Gastroenterol Hepatol. 2020 Dec;5(12):e8. doi: 10.1016/S2468-1253(20)30349-6.
7
Structured physical activity interventions as a complementary therapy for patients with inflammatory bowel disease - a scoping review and practical implications.结构型身体活动干预作为炎症性肠病患者的补充疗法——范围综述及实际意义。
BMC Gastroenterol. 2019 Jul 2;19(1):115. doi: 10.1186/s12876-019-1034-9.
8
The Association Between Sustained Poor Quality of Life and Future Opioid Use in Inflammatory Bowel Disease.持续性生活质量差与炎症性肠病患者未来阿片类药物使用的关联。
Inflamm Bowel Dis. 2018 Jun 8;24(7):1380-1388. doi: 10.1093/ibd/izy040.
9
Part 1: The Human Gut Microbiome in Health and Disease.第1部分:健康与疾病中的人类肠道微生物群
Integr Med (Encinitas). 2014 Dec;13(6):17-22.
10
Incorporating Yoga Therapy into Primary Care: The Casey Health Institute.将瑜伽疗法纳入初级保健:凯西健康研究所。
Int J Yoga Therap. 2015;25(1):43-9. doi: 10.17761/1531-2054-25.1.43.