巴西孢子丝菌传播的新见解
New Insights on Transmission of Sporothrix brasiliensis.
作者信息
Cognialli Regielly C R, Queiroz-Telles Flávio, Cavanaugh Alyson M, Rediguieri Bruno C, Santos Giovanna C D, Matias Felipe Moreira, Filho Luciano Moreira, Neto Elias N Monteiro, Surek Mônica, Vicente Vânia A, Santos-Weiss Izabella C R
机构信息
Hospital de Clínicas, Federal University of Paraná, Curitiba, Brazil.
Postgraduate Program in Microbiology, Parasitology and Pathology, Biological Sciences, Department of Basic Pathology, Federal University of Paraná, Curitiba, Brazil.
出版信息
Mycoses. 2025 Mar;68(3):e70047. doi: 10.1111/myc.70047.
BACKGROUND
Sporotrichosis is the most prevalent saprozoonotic implantation mycosis worldwide.
OBJECTIVES
A prospective experimental study was performed to evaluate persistence on surfaces such as stainless steel medium-density fiberboard (MDF) wood, tile, and polyester fabric.
METHODS
The different surfaces were homogeneously contaminated using the yeast phase of Sporothrix brasiliensis. Fungal culture was carried out in triplicate on Mycosel agar, at time 0 and then every 24 h, until 792 h (33 days).
RESULTS
Sporothrix brasiliensis persists on MDF wood for up to 240 h (10 days), tile for 288 h (12 days), polyester fabric for 384 h (16 days), and stainless steel for up to 600 h (25 days).
CONCLUSIONS
Based on these findings, in concordance with published clinical reports suggesting fomite transmission, we propose an updated schematic of S. brasiliensis transmission. This is the first in vitro study about the persistence of S. brasiliensis on different surfaces, which is essential to understand transmission routes for a One Health Approach.
背景
孢子丝菌病是全球最常见的腐生性植入性真菌病。
目的
进行一项前瞻性实验研究，以评估巴西孢子丝菌在不锈钢、中密度纤维板（MDF）、木材、瓷砖和聚酯织物等表面的存活时间。
方法
使用巴西孢子丝菌的酵母相均匀污染不同表面。在Mycosel琼脂上进行三次重复真菌培养，在0小时时进行，然后每24小时进行一次，直至792小时（33天）。
结果
巴西孢子丝菌在中密度纤维板上可存活长达240小时（10天），在瓷砖上为288小时（12天），在聚酯织物上为384小时（16天），在不锈钢上长达600小时（25天）。
结论
基于这些发现，与已发表的提示通过污染物传播的临床报告一致，我们提出了巴西孢子丝菌传播的更新示意图。这是关于巴西孢子丝菌在不同表面存活时间的首次体外研究，对于理解“同一健康”方法的传播途径至关重要。
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