Cognialli Regielly Caroline Raimundo, Taborda Matheus Hideki, Carneiro Bruno Hassunuma, do Prado Carolina Melchior, Wolski Mariana Marques, Breda Giovanni Luis, Spruijtenburg Bram, Vicente Vânia Aparecida, Meijer Eelco F J, de Queiroz-Telles Flávio
Hospital de Clínicas, Federal University of Paraná, Curitiba, Brazil.
Postgraduate Program in Microbiology, Parasitology and Pathology, Federal University of Paraná, Curitiba, Brazil.
Med Mycol Case Rep. 2025 Jun 30;49:100716. doi: 10.1016/j.mmcr.2025.100716. eCollection 2025 Sep.
Sporotrichosis is a growing public health concern especially due . We report a case of disseminated sporotrichosis involving the meninges, lungs, and testicles in a 35-year-old homeless man from Curitiba, Brazil. Fungal culture, histopathology, and molecular identification confirmed infection. Notably, testicular involvement-a rare complication of sporotrichosis-was initially misdiagnosed as a malignant tumor, leading to orchiectomy. A literature review identified only four previous cases of testicular sporotrichosis. This case underscores the potential for atypical presentations in immunocompromised patients and highlights the need for clinical vigilance in endemic regions, given the rising incidence of sporotrichosis.
孢子丝菌病正日益引起公众对健康的关注,尤其是因为……我们报告了一例播散性孢子丝菌病病例,患者为一名35岁来自巴西库里蒂巴的无家可归男子,累及脑膜、肺和睾丸。真菌培养、组织病理学和分子鉴定证实了感染。值得注意的是,睾丸受累——孢子丝菌病的一种罕见并发症——最初被误诊为恶性肿瘤,导致了睾丸切除术。文献回顾仅发现此前有4例睾丸孢子丝菌病病例。该病例强调了免疫功能低下患者出现非典型表现的可能性,并突出了鉴于孢子丝菌病发病率上升,在流行地区临床保持警惕的必要性。