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橄榄体脑桥小脑萎缩患者Meynert基底核的神经元丢失。

Neuronal loss in the basal nucleus of Meynert in a patient with olivopontocerebellar atrophy.

作者信息

Tagliavini F, Pilleri G

出版信息

Acta Neuropathol. 1985;66(2):127-33. doi: 10.1007/BF00688687.

DOI:10.1007/BF00688687
PMID:4013667
Abstract

A morphometric study of the basal nucleus of Meynert has been performed in a case of familial olivopontocerebellar atrophy with mental deterioration. The magnocellular population of the basal nucleus was found to be substantially reduced in number (over 60%) as compared with that of three age-matched controls. This finding has not been reported previously and might represent one of the anatomic substrates of some of the cognitive disturbances exhibited by a considerable number of patients with olivopontocerebellar atrophy (OPCA).

摘要

对一名伴有精神衰退的家族性橄榄体脑桥小脑萎缩患者的迈内特基底核进行了形态计量学研究。与三名年龄匹配的对照者相比,发现基底核的大细胞数量大幅减少(超过60%)。这一发现此前未见报道,可能是相当一部分橄榄体脑桥小脑萎缩(OPCA)患者所表现出的一些认知障碍的解剖学基础之一。

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Neuronal loss in the basal nucleus of Meynert in a patient with olivopontocerebellar atrophy.橄榄体脑桥小脑萎缩患者Meynert基底核的神经元丢失。
Acta Neuropathol. 1985;66(2):127-33. doi: 10.1007/BF00688687.
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Expression of the CD15 epitope in the human magnocellular basal forebrain system.

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The nucleus basalis in Alzheimer's disease: cell counts and cortical biochemistry.阿尔茨海默病中的基底核:细胞计数与皮质生物化学
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Pathological changes in the nucleus of Meynert in Alzheimer's and Parkinson's diseases.阿尔茨海默病和帕金森病中Meynert核的病理变化。
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