Joffres M, Reed D M, Nomura A M
Am J Epidemiol. 1985 Apr;121(4):488-500. doi: 10.1093/oxfordjournals.aje.a114027.
As part of the Honolulu Heart Program studies, 4,581 men of Japanese ancestry living in Hawaii completed a psychosocial questionnaire in 1971. By 1980, 280 new cancer cases had been recorded. Among 12 items related to stressful life situations, there were no consistent associations with total or site-specific cancer incidence. Most of the associations which were found were in the direction opposite to that predicted by the stress hypothesis. Among eight items related to social networks, two were significantly associated with total cancer incidence in multivariate analysis, but one of these associations was in the direction opposite to that of the social support hypothesis. Among the different measures of acculturation, there was a general pattern indicating that ties to traditional Japanese culture and diet were associated with an increased risk of cancer. Cancer incidence was associated with low levels of socioeconomic status. In general, there was little evidence to support the idea that either stressful or supportive life situations were associated with cancer incidence.
作为火奴鲁鲁心脏项目研究的一部分，1971年，居住在夏威夷的4581名日裔男性完成了一份社会心理调查问卷。到1980年，共记录了280例新的癌症病例。在与压力性生活状况相关的12项内容中，与总体或特定部位癌症发病率均无一致关联。所发现的大多数关联与压力假设所预测的方向相反。在与社交网络相关的8项内容中，多变量分析显示，有2项与总体癌症发病率显著相关，但其中1项关联与社会支持假设的方向相反。在不同的文化适应衡量指标中，总体模式表明，与传统日本文化和饮食的联系与癌症风险增加有关。癌症发病率与社会经济地位较低有关。总体而言，几乎没有证据支持压力或支持性的生活状况与癌症发病率有关的观点。
