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心肌梗死后患者在常氧和人工低氧条件下进行耐力训练的效果比较。

Comparison of the Effects of Endurance Training Conducted in Conditions of Normoxia and Artificial Hypoxia in Patients After Myocardial Infarction.

作者信息

Nowak-Lis Agata, Nowak Zbigniew, Grzybowska-Ganszczyk Dominika, Jastrzębski Paweł, Konarska-Rawluk Anna

机构信息

Department of Physiotherapy, Jerzy Kukuczka Academy of Physical Education, ul. Mikołowska 72a, 40-065 Katowice, Poland.

Department of Cardiology, Leszek Giec Upper-Silesian Medical Centre, Medical University of Silesia, ul. Bielska 4, 43-400 Cieszyn, Poland.

出版信息

J Clin Med. 2025 Mar 7;14(6):1790. doi: 10.3390/jcm14061790.

Abstract

: Attention should be paid to the introduction of more functional training methods during the second stage of cardiac rehabilitation, which imitate everyday activities to some extent. The main purpose of this research was to analyze the effects of a 22-day training program carried out in normobaric hypoxic conditions corresponding to the altitude of 3000 m a.s.l. in patients after myocardial infarction and to compare it with the same training conducted in normoxic conditions. : This study included 36 patients after myocardial infarction who underwent percutaneous angioplasty with stent implantation. They were examined before and after 2 days of training sessions: day one, spiroergometric exercise test on a mechanical treadmill, blood collection for laboratory tests; day two, echocardiography of the heart. Than patients underwent 22 days of training in hypoxic conditions. At the end of experiment patients had the same examinations as day one and two. : Training conducted in hypoxic conditions had a wider impact on spiroergometrical parameters. Significant, beneficial changes were demonstrated in relation to test duration, distance covered, energy expenditure MET, respiratory exchange ratio RER, as well as resting values of systolic and diastolic blood pressure. There were no changes in parameters for morphology, cytokines, and fibrinogen. There were some differences in relation to echocardiography examinations. : The conditions in which the rehabilitation training was conducted affect the level of exercise tolerance. The hypoxic conditions in which the training was conducted affected only two hemodynamic parameters: LVESd and e' septal. Rehabilitation training conducted in various environmental conditions had an impact only on the IL-10 value.

摘要

在心脏康复的第二阶段,应注重引入更多在一定程度上模仿日常活动的功能训练方法。本研究的主要目的是分析在相当于海拔3000米的常压低氧条件下进行的为期22天的训练计划对心肌梗死后患者的影响,并将其与在常氧条件下进行的相同训练进行比较。 本研究纳入了36例接受经皮血管成形术并植入支架的心肌梗死后患者。在训练课程的第2天前后对他们进行检查:第一天,在机械跑步机上进行运动心肺功能测试,采集血样进行实验室检查;第二天,进行心脏超声心动图检查。然后患者在低氧条件下进行22天的训练。实验结束时,患者进行与第一天和第二天相同的检查。 在低氧条件下进行的训练对运动心肺功能参数有更广泛的影响。在测试持续时间、覆盖距离、能量消耗代谢当量(MET)、呼吸交换率(RER)以及收缩压和舒张压的静息值方面显示出显著的有益变化。形态学、细胞因子和纤维蛋白原的参数没有变化。在超声心动图检查方面存在一些差异。 进行康复训练的条件会影响运动耐量水平。进行训练的低氧条件仅影响两个血流动力学参数:左室舒张末期内径(LVESd)和室间隔e'。在不同环境条件下进行的康复训练仅对白细胞介素-10值有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/11943074/ca4886288ef5/jcm-14-01790-g001.jpg

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