Department of Physical Education, Ocean University of China-Laoshan Campus, Qingdao 266100, China.
Int J Environ Res Public Health. 2021 Jun 23;18(13):6761. doi: 10.3390/ijerph18136761.
To investigate the effects of interval training (IT) as compared with continuous training (CT) on cardiorespiratory fitness and exercise tolerance of patients with heart failure (HF), with the aim to provide reasonable exercise prescriptions for patients with HF.
Through searching electronic databases, randomized controlled studies were collected. The included studies were evaluated for methodological quality using the Cochrane risk of bias assessment tool, and statistical analyses were carried out using Review Manager 5.3 and Stata MP 15.1 software.
A total of seventeen randomized controlled trials (i.e., studies) with 617 patients were included. The meta-analysis showed that IT can improve a patient's peak oxygen uptake (VO2peak) (MD = 2.08, 95% CI 1.16 to 2.99, < 0.00001), left ventricular ejection fraction (LVEF) (MD =1.32, 95% CI 0.60 to 2.03, = 0.0003), and 6-minute walk distance (6MWD) (MD = 25.67, 95% CI 12.87 to 38.47, < 0.0001) as compared with CT. However, for respiratory exchange ratio (RER) (MD = 0.00, 95% CI -0.02 to 0.03, = 0.81), CO ventilation equivalent slope (VE/VCO2 slope) (SMD = 0.04, 95% CI -0.23 to 0.31, = 0.75), and resting heart rate (HRrest) (MD = 0.15, 95% CI -3.00 to 3.29, = 0.93) there were no statistical significance.
The evidence shows that IT is better than CT for improving the cardiorespiratory fitness and exercise tolerance of patients with HF. Moreover, an intensity of 60-80% peak heart rate of IT is the optimal choice for patients. It is hoped that, in the future, more well-designed studies would further expand the meta-analysis results.
探讨间歇训练（IT）与连续训练（CT）相比对心力衰竭（HF）患者心肺功能和运动耐力的影响，旨在为 HF 患者提供合理的运动处方。
通过检索电子数据库，收集随机对照研究。使用 Cochrane 偏倚风险评估工具对纳入的研究进行方法学质量评估，并使用 Review Manager 5.3 和 Stata MP 15.1 软件进行统计分析。
共纳入 17 项随机对照试验（即研究），共 617 例患者。荟萃分析显示，IT 可提高患者峰值摄氧量（VO2peak）（MD = 2.08，95%CI 1.16 至 2.99，< 0.00001）、左心室射血分数（LVEF）（MD = 1.32，95%CI 0.60 至 2.03，= 0.0003）和 6 分钟步行距离（6MWD）（MD = 25.67，95%CI 12.87 至 38.47，< 0.0001），与 CT 相比。然而，对于呼吸交换率（RER）（MD = 0.00，95%CI -0.02 至 0.03，= 0.81）、CO 通气当量斜率（VE/VCO2 斜率）（SMD = 0.04，95%CI -0.23 至 0.31，= 0.75）和静息心率（HRrest）（MD = 0.15，95%CI -3.00 至 3.29，= 0.93），无统计学意义。
证据表明，IT 比 CT 更能改善 HF 患者的心肺功能和运动耐力。此外，IT 的强度为 60-80%峰值心率是患者的最佳选择。希望未来有更多设计良好的研究进一步扩大荟萃分析结果。
