Shirin Akter, Nadia Nusrat, Hossain Md Shahadat, Labony Sharmin Shahid, Ritu Sumaya Naznin, Ali Md Haydar, Islam Umme Razia, Parvin Romana, Esha Sadia Afroz, Dey Anita Rani, Alam Md Mahmudul, Alam Mohammad Zahangir, Alim Md Abdul
Department of Parasitology, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Department of Pathology and Parasitology, Hajee Mohammad Danesh Science and Technology University, Dinajpur, Bangladesh.
Parasitology. 2025 Apr;152(4):366-373. doi: 10.1017/S0031182025000319.
Helminth infection is highly prevalent in indigenous chickens reared in semi-scavenging/ scavenging systems in Bangladesh. Here, we estimated the prevalence of gizzard worm infection in indigenous chickens, the detection of the worm-induced pathologies, the development of cultural protocol, and anthelmintic efficacy. We randomly collected and examined 390 chickens and isolated worms from the gizzard and proventriculus. The isolated worms were identified as Diesing, 1861. The overall prevalence of was 33.1% (129 out of 390). Prevalence of the worm was almost similar in both sexes but significantly (p <0.05) higher in adult chickens (44.3%) and in the summer season (47.1%). In heavy infections, destroyed the muscular layer of the gizzard. The presence of brown necrotic tissues and curd-like caseous materials was detected in the affected gizzards. In severe cases, the horny lining of the gizzard was inflamed, necrotized and marked by multiple holes and brick-red colored spots. Liquefied, fetid materials oozed out from the muscular layer in extensive cases. Histopathological examination showed marked infiltrations of eosinophils. In serum-supplemented M199 and DMEM, adult survived well and reproduced. Levamisole (LEV) and ivermectin (IVM) efficiently killed the worm. However, albendazole (ABZ), mebendazole (MBZ) and piperazine (PPZ) did not kill the worms. Our results suggest that is highly prevalent in semi-scavenging chickens in Bangladesh. LEV and IVM can be used to treat and control the infection in chickens.
蠕虫感染在孟加拉国以半放养/放养方式饲养的本地鸡中非常普遍。在此，我们估计了本地鸡中砂囊蠕虫感染的流行率、蠕虫引起的病变检测、培养方案的制定以及驱虫药的疗效。我们随机收集并检查了390只鸡，从砂囊和腺胃中分离出蠕虫。分离出的蠕虫被鉴定为1861年的迪辛属。总体流行率为33.1%（390只中有129只）。蠕虫在两性中的流行率几乎相似，但成年鸡（44.3%）和夏季（47.1%）的流行率显著更高（p<0.05）。在重度感染中，蠕虫破坏了砂囊的肌肉层。在受影响的砂囊中检测到棕色坏死组织和凝乳状干酪样物质。在严重病例中，砂囊的角质内衬发炎、坏死，有多个孔洞和砖红色斑点。在广泛病例中，液化的恶臭物质从肌肉层渗出。组织病理学检查显示嗜酸性粒细胞明显浸润。在添加血清的M199和DMEM中，成年蠕虫存活良好并繁殖。左旋咪唑（LEV）和伊维菌素（IVM）能有效杀死蠕虫。然而，阿苯达唑（ABZ）、甲苯达唑（MBZ）和哌嗪（PPZ）不能杀死蠕虫。我们的结果表明，蠕虫在孟加拉国的半放养鸡中高度流行。LEV和IVM可用于治疗和控制鸡的感染。
