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心脏和肾脏移植后的妊娠:一例病例报告。

Pregnancy after heart and kidney transplantation: a case report.

作者信息

Ahmadi Farnaz, Naghashzadeh Farah, Ahmadi Zargham Hossein, Sharif-Kashani Babak, Nejatollahi Seyed Mohammad Reza, Khodadad Shakiba, Mirhossein Seyed Mohsen, Ansari Aval Zahra, Jahangirifard Alireza, Saliminejad Leila, Sharif-Kashani Sourena, Shafaghi Shadi, Noorali Sima

机构信息

Lung Transplantation Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

JHLT Open. 2024 Jan 23;4:100059. doi: 10.1016/j.jhlto.2024.100059. eCollection 2024 May.

Abstract

BACKGROUND

The risk of pregnancy-associated complications is considerably elevated in transplant recipients compared to the general population, and it should be managed aggressively to preserve the allograft function and avoid complications. In the present case report, we described a 24-year-old woman with a transplanted heart and kidney who got pregnant after 6 years.

CASE PRESENTATION

A 24-year-old female who was diagnosed with congenital dilated cardiomyopathy and end-stage renal disease due to reflux nephropathy underwent combined heart and kidney transplantation. In her follow-up, she experienced pregnancy after 6 years. Afterward, a multidisciplinary team of different specialists monitored the pregnancy. After 40 weeks of pregnancy, a cesarean section was performed with obtaining a live female sex newborn with a weight of 2450 g, height of 50 cm, and Apgar score of 9, without any congenital malformations. In the follow-up, after 5 years, normal growth and development without any malformations and congenital disorders were observed.

CONCLUSION

The successful outcome of pregnancy in this woman could be due to the proper cooperation between the medical team and patient, and also the appropriate timing of pregnancy.

摘要

背景

与普通人群相比,移植受者发生妊娠相关并发症的风险显著升高,应积极管理以维持移植器官功能并避免并发症。在本病例报告中,我们描述了一名24岁接受心脏和肾脏移植的女性,她在术后6年怀孕。

病例介绍

一名24岁女性,因反流性肾病被诊断为先天性扩张型心肌病和终末期肾病,接受了心脏和肾脏联合移植。在随访过程中,她在6年后怀孕。此后,由不同专科医生组成的多学科团队对其妊娠情况进行监测。妊娠40周后,进行了剖宫产,产下一名体重2450克、身高50厘米、阿氏评分9分的活女婴,无任何先天性畸形。在随访中,5年后观察到其生长发育正常,无任何畸形和先天性疾病。

结论

该女性妊娠成功的结果可能得益于医疗团队与患者之间的良好合作,以及合适的妊娠时机。

相似文献

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Pregnancy after heart and kidney transplantation: a case report.心脏和肾脏移植后的妊娠:一例病例报告。
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本文引用的文献

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Pregnancy in chronic kidney disease and kidney transplantation.慢性肾脏病和肾移植中的妊娠。
Kidney Int. 2017 May;91(5):1047-1056. doi: 10.1016/j.kint.2016.10.045. Epub 2017 Feb 13.
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The impact of dasatinib on pregnancy outcomes.达沙替尼对妊娠结局的影响。
Am J Hematol. 2015 Dec;90(12):1111-5. doi: 10.1002/ajh.24186. Epub 2015 Oct 12.
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Management of pregnancy in the post-cardiac transplant patient.心脏移植术后患者的妊娠管理
Semin Perinatol. 2014 Aug;38(5):318-25. doi: 10.1053/j.semperi.2014.04.022. Epub 2014 Jun 25.
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Pregnancy in renal transplant recipients: a UK national cohort study.肾移植受者的妊娠:一项英国全国队列研究。
Clin J Am Soc Nephrol. 2013 Feb;8(2):290-8. doi: 10.2215/CJN.06170612. Epub 2012 Oct 18.

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