Nef is a key player in neuroinflammation and myelin impairment associated with neuroHIV.
作者信息
Bukrinsky Michael Ilya
机构信息
School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States.
出版信息
Front Neurol. 2025 Mar 12;16:1553594. doi: 10.3389/fneur.2025.1553594. eCollection 2025.
Abstract
摘要
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本文引用的文献
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The Yin and Yang of Microglia-Derived Extracellular Vesicles in CNS Injury and Diseases.小胶质细胞衍生细胞外囊泡在中枢神经系统损伤和疾病中的阴阳两面。
Cells. 2024 Nov 6;13(22):1834. doi: 10.3390/cells13221834.
2
Nef mediates neuroimmune response, myelin impairment, and neuronal injury in EcoHIV-infected mice.Nef 介导 EcoHIV 感染小鼠的神经免疫反应、髓鞘损伤和神经元损伤。
Life Sci Alliance. 2024 Nov 12;8(2). doi: 10.26508/lsa.202402879. Print 2025 Feb.
3
HIV-associated neurocognitive disorder: key implications of the microbiota-gut-brain axis.人类免疫缺陷病毒相关神经认知障碍：微生物群-肠道-脑轴的关键影响
Front Microbiol. 2024 Aug 2;15:1428239. doi: 10.3389/fmicb.2024.1428239. eCollection 2024.
4
Gene expression and chromatin conformation of microglia in virally suppressed people with HIV.HIV 感染者病毒抑制后的小胶质细胞的基因表达和染色质构象。
Life Sci Alliance. 2024 Jul 26;7(10). doi: 10.26508/lsa.202402736. Print 2024 Oct.
5
HIV-1 Nef is carried on the surface of extracellular vesicles.HIV-1 Nef存在于细胞外囊泡表面。
J Extracell Vesicles. 2024 Jul;13(7):e12478. doi: 10.1002/jev2.12478.
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EcoHIV Infection of Primary Murine Brain Cell Cultures to Model HIV Replication and Neuropathogenesis.用原代鼠脑细胞培养物进行生态 HIV 感染，以模拟 HIV 复制和神经发病机制。
Viruses. 2024 Apr 27;16(5):693. doi: 10.3390/v16050693.
7
Extracellular vesicles produced by HIV-1 Nef-expressing cells induce myelin impairment and oligodendrocyte damage in the mouse central nervous system.HIV-1 Nef 表达细胞产生的细胞外囊泡可诱导小鼠中枢神经系统髓鞘损伤和少突胶质细胞损伤。
J Neuroinflammation. 2024 May 13;21(1):127. doi: 10.1186/s12974-024-03124-5.
8
HIV-Associated Neurocognitive Disorder: A Look into Cellular and Molecular Pathology.HIV 相关神经认知障碍：细胞与分子病理学研究。
Int J Mol Sci. 2024 Apr 25;25(9):4697. doi: 10.3390/ijms25094697.
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Mol Neurobiol. 2024 Nov;61(11):9320-9346. doi: 10.1007/s12035-024-04173-w. Epub 2024 Apr 17.
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