Young R C, Alexopoulos G S, Shamoian C A, Kent E, Dhar A K, Kutt H
Am J Psychiatry. 1985 Jul;142(7):866-8. doi: 10.1176/ajp.142.7.866.
Among 18 elderly depressed patients given ECGs before and during nortriptyline treatment, plasma E-10-hydroxynortriptyline and the sum of E-10-hydroxynortriptyline and nortriptyline distinguished the group with conduction/repolarization effects. Plasma nortriptyline, age, drug dose, and baseline cardiovascular status did not.
