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Cell Phf8 ['feɪt] control: Epigenetic regulation during oligodendroglial development.

作者信息

Kremp Marco, Wegner Michael

机构信息

Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

出版信息

Neural Regen Res. 2026 Mar 1;21(3):1110-1111. doi: 10.4103/NRR.NRR-D-24-01414. Epub 2025 Mar 25.

DOI:10.4103/NRR.NRR-D-24-01414
PMID:40145966
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12296415/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f86/12296415/768c640b994f/NRR-21-1110-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f86/12296415/0dc0ecbedb3d/NRR-21-1110-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f86/12296415/768c640b994f/NRR-21-1110-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f86/12296415/0dc0ecbedb3d/NRR-21-1110-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f86/12296415/768c640b994f/NRR-21-1110-g002.jpg

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Cell Phf8 ['feɪt] control: Epigenetic regulation during oligodendroglial development.细胞Phf8 [发音为“feɪt”] 调控：少突胶质细胞发育过程中的表观遗传调控
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本文引用的文献

1
Transcription factor Olig2 is a major downstream effector of histone demethylase Phf8 during oligodendroglial development.转录因子Olig2是少突胶质细胞发育过程中组蛋白去甲基化酶Phf8的主要下游效应因子。
Glia. 2024 Aug;72(8):1435-1450. doi: 10.1002/glia.24538. Epub 2024 Apr 13.
2
The histone demethylase PHF8 regulates astrocyte differentiation and function.组蛋白去甲基化酶PHF8调节星形胶质细胞的分化和功能。
Development. 2021 Jun 15;148(12). doi: 10.1242/dev.194951. Epub 2021 Jun 28.
3
Impact of the Olig Family on Neurodevelopmental Disorders.
奥立格家族对神经发育障碍的影响。
Front Neurosci. 2021 Mar 30;15:659601. doi: 10.3389/fnins.2021.659601. eCollection 2021.
4
PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway.PRC2 作为一个关键的计时器，通过抑制 Notch 通路来驱动少突胶质细胞命运而非星形胶质细胞特性。
Cell Rep. 2020 Sep 15;32(11):108147. doi: 10.1016/j.celrep.2020.108147.
5
Chromatin remodelers in oligodendroglia.少突胶质细胞中的染色质重塑因子
Glia. 2020 Aug;68(8):1604-1618. doi: 10.1002/glia.23837. Epub 2020 May 27.
6
Epigenetic regulation of oligodendrocyte myelination in developmental disorders and neurodegenerative diseases.发育障碍和神经退行性疾病中少突胶质细胞髓鞘形成的表观遗传调控
F1000Res. 2020 Feb 11;9. doi: 10.12688/f1000research.20904.1. eCollection 2020.
7
Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway.PHF8组蛋白去甲基化酶缺乏通过mTOR途径导致认知障碍。
Nat Commun. 2018 Jan 9;9(1):114. doi: 10.1038/s41467-017-02531-y.
8
Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation.少突胶质细胞分化过程中由抑制性组蛋白甲基化定义的染色质景观。
J Neurosci. 2015 Jan 7;35(1):352-65. doi: 10.1523/JNEUROSCI.2606-14.2015.
9
Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes.Ezh2 基因占据的动态变化是其参与神经干细胞自我更新和向少突胶质细胞分化的基础。
PLoS One. 2012;7(7):e40399. doi: 10.1371/journal.pone.0040399. Epub 2012 Jul 12.
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Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain.组蛋白修饰影响发育中大鼠大脑少突胶质细胞祖细胞分化的时间。
J Cell Biol. 2005 May 23;169(4):577-89. doi: 10.1083/jcb.200412101. Epub 2005 May 16.