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气候变化与过敏和哮喘的未来

Climate Change and the Future of Allergies and Asthma.

作者信息

Burbank Allison J

机构信息

Division of Pediatric Allergy and Immunology, University of North Carolina, Mary Ellen Jones Bldg, 5008B 116 Manning Dr, CB#7231, Chapel Hill, NC, 27599, USA.

出版信息

Curr Allergy Asthma Rep. 2025 Mar 27;25(1):20. doi: 10.1007/s11882-025-01201-0.

Abstract

PURPOSE OF THIS REVIEW

Climate change affects global temperature, meteorological variables, plant aerobiology, air pollution exposure and a host of other factors that individually have been implicated in the inception and/or exacerbation of allergic disease like asthma and allergic rhinitis. It is unknown how climate change will impact allergic disease prevalence and morbidity in the future.

RECENT FINDINGS

Pollen seasons are lengthening with variable effects on pollen peak concentrations and allergenicity. Air pollution exposure is linked with enhance susceptibility to allergic inflammation induced by pollen and with enhanced susceptibility to infection with a morbidity/mortality from respiratory viruses, including SARS-CoV-2. The available literature largely supports the association between climate change and three of the most salient factors for allergic respiratory disease prevalence and morbidity: changes in allergen exposure, pollution exposure, and viral respiratory infection. More research is needed to understand the complex interactions between these factors and individual-level variables that influence disease susceptibility.

摘要

本综述的目的

气候变化影响全球气温、气象变量、植物空气生物学、空气污染暴露以及许多其他因素,这些因素各自都与哮喘和过敏性鼻炎等过敏性疾病的发生和/或加重有关。目前尚不清楚气候变化未来将如何影响过敏性疾病的患病率和发病率。

最新发现

花粉季节正在延长,对花粉峰值浓度和致敏性有不同影响。空气污染暴露与对花粉诱导的过敏性炎症易感性增加以及对包括SARS-CoV-2在内的呼吸道病毒感染导致的发病/死亡易感性增加有关。现有文献在很大程度上支持气候变化与过敏性呼吸道疾病患病率和发病率的三个最显著因素之间的关联:过敏原暴露变化、污染暴露和病毒性呼吸道感染。需要更多研究来了解这些因素与影响疾病易感性的个体水平变量之间的复杂相互作用。

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