Yiying Wang, Shuai Dong, Bo L I, Mei Han, Huijuan Cao
Center for Evidence-Based Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
J Tradit Chin Med. 2025 Apr;45(2):234-253. doi: 10.19852/j.cnki.jtcm.2025.02.002.
To update the current best evidence on the effectiveness and safety of cupping therapy in pain management.
The protocol of this systematic review was registered at PROSPERO (CRD42021261308). An updated literature searching in 7 databases was conducted from January 2014 to January 2023. Two authors extracted data and assessed the risk of bias independently. Statistical analysis was performed using RevMan 5.4.1 software (Cochrane Collaboration, London, UK). Meta-analysis with a random effect model was conducted when there was no serious statistical heterogeneity among trials (2≤75%). Grading of Recommendations Assessment, Development, and Evaluation was also conducted to assess the quality of evidence.
Seventy-two trials with 5720 participants were included. All included trials were assessed as having high risk of bias. The majority of the included trials reported the benefit of cupping plus other therapy or cupping alone on improving cure rate (average risk ratio more than 1.15) and reducing visual analogue scale [average mean difference () reduction 0.16 to 7.0 cm], improving quality of life, quality of sleep or other symptoms related to pain condition. And there was low/very low quality evidence that the incidence of adverse events in the cupping groups were lower than that in the control groups. Although the heterogeneity between studies and the methodological quality of the study itself lead to the low evidence strength of the current conclusions, the results of this study are a valuable supplement to the founding of previous review.
Cupping therapy alone or combined with other therapy was considered benefit in relieving pain, improving the quality of life, and increasing the cure rate of patients with pain conditions, though supported by the low quality of evidence. According to the limited evidence, cupping therapy seems to have less harm than drugs when treating pain conditions.
更新拔罐疗法在疼痛管理中有效性和安全性的当前最佳证据。
本系统评价的方案已在国际前瞻性系统评价注册库（PROSPERO，注册号：CRD42021261308）登记。于2014年1月至2023年1月在7个数据库中进行了文献更新检索。两名作者独立提取数据并评估偏倚风险。使用RevMan 5.4.1软件（英国伦敦Cochrane协作网）进行统计分析。当各试验间无严重统计学异质性（I²≤75%）时，采用随机效应模型进行Meta分析。还进行了推荐意见评估、制定与评价分级（GRADE）以评估证据质量。
纳入72项试验，共5720名参与者。所有纳入试验均被评估为具有高偏倚风险。大多数纳入试验报告了拔罐联合其他疗法或单独拔罐在提高治愈率（平均风险比大于1.15）以及降低视觉模拟评分[平均差值（MD）降低0.16至7.0 cm]、改善生活质量、睡眠质量或与疼痛状况相关的其他症状方面的益处。并且有低/极低质量证据表明拔罐组不良事件的发生率低于对照组。尽管研究间的异质性以及研究本身的方法学质量导致当前结论的证据强度较低，但本研究结果是对既往综述结果的有价值补充。
单独或联合其他疗法的拔罐疗法被认为在缓解疼痛、改善生活质量以及提高疼痛患者治愈率方面有益，尽管证据质量较低。根据有限的证据，拔罐疗法在治疗疼痛状况时似乎比药物危害更小。
