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一名接受结核病治疗的HIV阳性患者发生药物性狼疮:病例报告

Drug-Induced Lupus in an HIV-Positive Patient Treated for Tuberculosis: A Case Report.

作者信息

Mahmud Omar, Jahangir Arshia, Waqas Syed Muhammad, Nasir Noreen

机构信息

Medical College, Aga Khan University, Karachi, Pakistan.

Section of Internal Medicine, Department of Medicine, Aga Khan University, Karachi, Pakistan.

出版信息

Clin Med Insights Case Rep. 2025 Mar 27;18:11795476251329232. doi: 10.1177/11795476251329232. eCollection 2025.

Abstract

The accurate diagnosis of pathologies with obscure presentations requires comprehensive clinical evaluation, epidemiological context, and consideration of the patient's clinical or hospital course. In this case report, we describe a 30-year-old female receiving antituberculosis therapy who developed multiple signs and symptoms that were unexplained by any single diagnosis, including multiple rashes with different features. The patient was determined to have drug induced lupus with concomitant HIV infection. Physicians should consider the possibility of co-existing disease processes when a single unifying diagnosis that reconciles all aspects of the patient's presentation cannot be identified.

摘要

对于表现隐匿的病症进行准确诊断需要全面的临床评估、流行病学背景以及对患者临床或住院病程的考量。在本病例报告中,我们描述了一名正在接受抗结核治疗的30岁女性,她出现了多种无法用单一诊断解释的体征和症状,包括多种具有不同特征的皮疹。该患者被诊断为药物性狼疮合并HIV感染。当无法确定一个能解释患者所有临床表现的统一诊断时,医生应考虑并存疾病过程的可能性。

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