Senescence at the Crossroads of Lung Development and Injury.
作者信息
Willis Kent A, Ambalavanan Namasivayam
机构信息
Heersink School of Medicine University of Alabama at Birmingham Birmingham, Alabama.
出版信息
Am J Respir Cell Mol Biol. 2025 Aug;73(2):161-162. doi: 10.1165/rcmb.2024-0564ED.
Abstract
摘要
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本文引用的文献
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Elevated Senescence Markers in Developing Trisomy 21 Human Lungs.发育中的21三体人类肺部衰老标志物升高。
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2
Senescence as a therapeutic target in cancer and age-related diseases.衰老作为癌症和年龄相关疾病的治疗靶点。
Nat Rev Drug Discov. 2025 Jan;24(1):57-71. doi: 10.1038/s41573-024-01074-4. Epub 2024 Nov 15.
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Cellular senescence in chronic lung diseases from newborns to the elderly: An update literature review.从新生儿到老年人的慢性肺部疾病中的细胞衰老：更新文献综述。
Biomed Pharmacother. 2024 Apr;173:116463. doi: 10.1016/j.biopha.2024.116463. Epub 2024 Mar 18.
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Small airway fibroblasts from patients with chronic obstructive pulmonary disease exhibit cellular senescence.慢性阻塞性肺疾病患者的小气道成纤维细胞表现出细胞衰老。
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Role of mitochondrial fusion proteins MFN2 and OPA1 on lung cellular senescence in chronic obstructive pulmonary disease.线粒体融合蛋白MFN2和OPA1在慢性阻塞性肺疾病肺细胞衰老中的作用
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Biomedicines. 2023 Jul 23;11(7):2072. doi: 10.3390/biomedicines11072072.
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Timing and cell specificity of senescence drives postnatal lung development and injury.衰老的时间和细胞特异性驱动出生后肺发育和损伤。
Nat Commun. 2023 Jan 17;14(1):273. doi: 10.1038/s41467-023-35985-4.
8
COPD-derived fibroblasts secrete higher levels of senescence-associated secretory phenotype proteins.COPD 相关成纤维细胞分泌更高水平的衰老相关 secretory phenotype 蛋白。
Thorax. 2021 May;76(5):508-511. doi: 10.1136/thoraxjnl-2020-215114. Epub 2020 Dec 3.
9
Cellular senescence in the lung across the age spectrum.肺部细胞衰老与年龄相关。
Am J Physiol Lung Cell Mol Physiol. 2019 May 1;316(5):L826-L842. doi: 10.1152/ajplung.00424.2018. Epub 2019 Feb 20.
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A role for cellular senescence in birth timing.细胞衰老在出生时间中的作用。
Cell Cycle. 2017;16(21):2023-2031. doi: 10.1080/15384101.2017.1371888. Epub 2017 Sep 25.
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