Soleimani Azam, Khademi Fatemeh Sadat, Soleimani Zahra, Paknahad Mohammad Hossein, Roohafza Hamidreza, Sadeghi Masoumeh
Cardiac Rehabilitation Department, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Chamran Cardiovascular Medical and Research Center, Echocardiography Department, Isfahan University of Medical Sciences, Isfahan, Iran.
Medicine (Baltimore). 2025 Mar 28;104(13):e41974. doi: 10.1097/MD.0000000000041974.
This study explored connections between women's reproductive factors and acute ST-segment elevation myocardial infarction (STEMI). A retrospective case-control study was conducted between 2016 and 2017. The study included 110 women diagnosed with STEMI and 110 control participants. Data on reproductive factors were collected through structured questionnaires and analyzed using statistical methods. Findings showed that increased STEMI risk was associated with longer lactation period, a higher number of parities, gravidity, and abortions. No significant relationships were observed for menopausal status, menopausal age, menarche age, reproductive duration, or oral contraceptive use. This study revealed that higher gravidity, parity, history of abortion, and longer breastfeeding duration were linked to an increased risk of STEMI. However, no significant differences were found between the case and control groups regarding menopausal status, age at menopause, age at menarche, reproductive duration, or oral contraceptive use.
本研究探讨了女性生殖因素与急性ST段抬高型心肌梗死（STEMI）之间的联系。2016年至2017年进行了一项回顾性病例对照研究。该研究纳入了110名诊断为STEMI的女性和110名对照参与者。通过结构化问卷收集生殖因素数据，并采用统计方法进行分析。研究结果显示，STEMI风险增加与哺乳期延长、产次、妊娠次数和流产次数增多有关。在绝经状态、绝经年龄、初潮年龄、生殖持续时间或口服避孕药使用方面未观察到显著关系。本研究表明，较高的妊娠次数、产次、流产史和较长的母乳喂养持续时间与STEMI风险增加有关。然而，在病例组和对照组之间，绝经状态、绝经年龄、初潮年龄、生殖持续时间或口服避孕药使用方面未发现显著差异。
