Zbinden A M, Frei F J, Funk B, Thomson D A, Westenskow D
Br J Anaesth. 1985 Aug;57(8):796-802. doi: 10.1093/bja/57.8.796.
A gas chromatographic method is described for the direct quantitative determination of the partial pressure of halothane (or isoflurane) in blood as well as the blood-gas partition coefficient. A head space technique and a flame ionization detector were used. Standard blood was obtained by equilibrating patients' blood with known gas concentrations in a tonometer. Using an infra-red analyser to measure the halothane gas concentration in the tonometer and within the anaesthetic system allowed for the direct comparison of the partial pressure in blood to the partial pressure in the inspired gas. Technical problems associated with this procedure, and with comparable methods, are discussed.
本文描述了一种气相色谱法，用于直接定量测定血液中氟烷（或异氟烷）的分压以及血气分配系数。采用了顶空技术和火焰离子化检测器。通过在张力计中用已知气体浓度平衡患者血液来获得标准血液。使用红外分析仪测量张力计和麻醉系统内的氟烷气体浓度，以便直接比较血液中的分压与吸入气体中的分压。讨论了与该程序以及类似方法相关的技术问题。
