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左大腿特发性肿瘤性钙化症:一例报告

Idiopathic tumoral calcinosis of the left thigh: a case report.

作者信息

Eldirdiri Sami, Eldirdiri Samaual, Elbashir Ibrahim B A, Aldaw Nahid F, Abd Allah Hind M A, Ibrahim Mohamed Y

机构信息

Department of Surgery, University of Gadarif, Gadarif, Sudan.

Department of Orthopedic Surgery, University of Gadarif, Gadarif, Sudan.

出版信息

J Surg Case Rep. 2025 Mar 28;2025(4):rjaf171. doi: 10.1093/jscr/rjaf171. eCollection 2025 Apr.

DOI:10.1093/jscr/rjaf171
PMID:40161886
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11952900/
Abstract

Idiopathic tumoral calcinosis is a very rare benign condition characterized by pathological deposition of calcium phosphate crystals into the soft tissues, particularly into the peri-articular regions. This case report narrates the first reported case of idiopathic tumoral calcinosis in Sudan. A 38-year-old Sudanese female from Gadarif presented with a history of progressive enlargement of the left thigh swelling over a period of 1 year, which was painless. Clinical examination revealed a firm and well-circumscribed mass without overlying skin changes. Imaging revealed calcification with a characteristic "chicken wire" pattern in X-rays, and histopathology confirmed lobulated calcium deposits surrounded by fibrous tissue and foreign body giant cell reactions without malignancy. The patient underwent complete surgical excision of the mass under spinal anesthesia, and her recovery was uneventful. This case highlights the need for recognition of idiopathic tumoral calcinosis in the differential diagnosis of soft tissue masses, especially in the region where these are underreported.

摘要

特发性肿瘤性钙化是一种非常罕见的良性疾病,其特征是磷酸钙晶体在软组织中病理性沉积,尤其是在关节周围区域。本病例报告讲述了苏丹首例特发性肿瘤性钙化的报道病例。一名来自加达里夫的38岁苏丹女性,有左大腿肿物在1年时间里逐渐增大的病史,肿物无痛。临床检查发现一个质地硬且边界清晰的肿块,表面皮肤无变化。影像学检查在X线片上显示出具有特征性“铁丝网”样的钙化,组织病理学证实为分叶状钙沉积,周围有纤维组织和异物巨细胞反应,无恶性病变。患者在脊髓麻醉下接受了肿物的完整手术切除,术后恢复顺利。本病例强调了在软组织肿块的鉴别诊断中,尤其是在这些病例报告较少的地区,认识特发性肿瘤性钙化的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/343d/11952900/e7cb2a7e4de2/rjaf171f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/343d/11952900/8cd3a4bd3673/rjaf171f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/343d/11952900/0a4092be42db/rjaf171f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/343d/11952900/e7cb2a7e4de2/rjaf171f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/343d/11952900/8cd3a4bd3673/rjaf171f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/343d/11952900/0a4092be42db/rjaf171f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/343d/11952900/e7cb2a7e4de2/rjaf171f3.jpg

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本文引用的文献

1
Tumoral calcinosis in chronic renal failure: A case report and literature review.慢性肾衰竭中的肿瘤性钙化:一例报告及文献综述
Int J Surg Case Rep. 2024 Oct;123:110237. doi: 10.1016/j.ijscr.2024.110237. Epub 2024 Sep 6.
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A rare case of idiopathic tumoral calcinosis: Case report.一例罕见的特发性肿瘤性钙化症:病例报告。
Radiol Case Rep. 2022 Sep 15;17(11):4350-4353. doi: 10.1016/j.radcr.2022.08.038. eCollection 2022 Nov.
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Pathologic Fracture of Femoral Neck in a Patient with Tumoral Calcinosis.肿瘤性钙化症患者的股骨颈病理性骨折
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Radiol Case Rep. 2017 May 3;12(3):560-563. doi: 10.1016/j.radcr.2017.03.023. eCollection 2017 Sep.
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Idiopathic Tumoral Calcinosis - Rare Clinico Pathological Entity: A Report of Two Cases.特发性肿瘤性钙化症——罕见的临床病理实体:两例报告
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