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Potential of Depth-of-Interaction-Based Detection Time Correction in Cherenkov Emitter Crystals for TOF-PET.基于相互作用深度的切伦科夫发射体晶体中飞行时间正电子发射断层扫描探测时间校正的潜力
IEEE Trans Radiat Plasma Med Sci. 2023 Mar;7(3):233-240. doi: 10.1109/trpms.2022.3226950. Epub 2022 Dec 6.
2
Ultrafast timing enables reconstruction-free positron emission imaging.超快计时实现无需重建的正电子发射成像。
Nat Photonics. 2021 Dec;15(12):914-918. doi: 10.1038/s41566-021-00871-2. Epub 2021 Oct 14.
3
High resolution detectors for whole-body PET scanners by using dual-ended readout.采用双端读出的全身正电子发射断层扫描仪高分辨率探测器。
EJNMMI Phys. 2022 Apr 21;9(1):29. doi: 10.1186/s40658-022-00460-4.
4
Understanding the intrinsic radioactivity energy spectrum from Lu in LYSO/LSO scintillation crystals.了解LYSO/LSO闪烁晶体中镥的本征放射性能谱。
Sci Rep. 2018 Nov 23;8(1):17310. doi: 10.1038/s41598-018-35684-x.
5
Advanced optical simulation of scintillation detectors in GATE V8.0: first implementation of a reflectance model based on measured data.GATE V8.0中闪烁探测器的高级光学模拟:基于测量数据的反射率模型的首次实现。
Phys Med Biol. 2017 Jun 21;62(12):L1-L8. doi: 10.1088/1361-6560/aa7007. Epub 2017 Apr 28.
6
An integrated model of scintillator-reflector properties for advanced simulations of optical transport.用于光学传输高级模拟的闪烁体-反射器特性集成模型。
Phys Med Biol. 2017 Jun 21;62(12):4811-4830. doi: 10.1088/1361-6560/aa6ca5. Epub 2017 Apr 11.
7
Simulation of light transport in scintillators based on 3D characterization of crystal surfaces.基于晶体表面三维特征的闪烁体中光传输的模拟。
Phys Med Biol. 2013 Apr 7;58(7):2185-98. doi: 10.1088/0031-9155/58/7/2185. Epub 2013 Mar 11.

将光子晶体应用于用于门模拟的戴维斯查找表模块中。

Implementation of Photonic Crystals into Davis LUT module for GATE simulation.

作者信息

He Xuzhi, Trigila Carlotta, Roncali Emilie

机构信息

Department of Biomedical Engineering at the University of California Davis, Davis, CA 95616 USA.

出版信息

IEEE Trans Radiat Plasma Med Sci. 2025 Mar;9(3):269-276. doi: 10.1109/trpms.2024.3501373. Epub 2024 Nov 18.

DOI:10.1109/trpms.2024.3501373
PMID:40162343
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11951240/
Abstract

The performance of Positron Emission Tomography (PET) detectors has been constrained by the photodetector collection of optical photons emitted in the scintillator, which was limited to photons reaching the exit surface with an angle larger than the critical angle. Photonic Crystals (PhCs) are periodic nanostructures with sizes comparable to the optical photons' wavelengths, which can break through the critical angle limit. Thorough experimental investigation of PhCs effect on optical harvest in scintillator detectors is complex and costly. Simulation can overcome these challenges. Mainstream software such as GATE does not support PhCs simulation. Here, we generalize the GATE optical model by incorporating the PhCs optical model into the LUT Davis model. We can model the performance of advanced scintillator detectors via the generalized LUT Davis model. The scintillator and PhCs materials tested in this work were lutetium oxyorthosilicate and titanium dioxide, respectively. Scintillators with a cross-section of 3×3 mm or 10×10 mm and a thickness varying from 9 mm to 18 mm with a step size of 3 mm were modeled with a PhCs interface to the photodetector. Among the 4 tested PhCs configurations, the best optical photon harvest was improved by 62.4% compared to traditional coupling with variable results between PhCs structures. The energy resolution only slightly improved. We thus investigated the angular distribution of collected optical photons, which can guide the optimization of photodetectors' detection efficiency at specific angles.

摘要

正电子发射断层扫描(PET)探测器的性能一直受到闪烁体中发射的光学光子的光电探测器收集效率的限制,这种限制仅限于以大于临界角的角度到达出射表面的光子。光子晶体(PhC)是尺寸与光学光子波长相当的周期性纳米结构,它可以突破临界角限制。对光子晶体对闪烁体探测器中光学收获的影响进行全面的实验研究既复杂又昂贵。模拟可以克服这些挑战。诸如GATE之类的主流软件不支持光子晶体模拟。在这里,我们通过将光子晶体光学模型纳入LUT Davis模型来推广GATE光学模型。我们可以通过广义LUT Davis模型对先进闪烁体探测器的性能进行建模。在这项工作中测试的闪烁体和光子晶体材料分别是正硅酸镥和二氧化钛。对横截面为3×3毫米或10×10毫米、厚度从9毫米到18毫米(步长为3毫米)的闪烁体,用与光电探测器的光子晶体界面进行建模。在4种测试的光子晶体配置中,与传统耦合相比,最佳光学光子收获提高了62.4%,不同光子晶体结构之间的结果有所不同。能量分辨率仅略有提高。因此,我们研究了收集到的光学光子的角分布,这可以指导在特定角度优化光电探测器的探测效率。