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心理干预对晚期结肠癌患者负面情绪、疼痛及睡眠的影响

The effects of psychological intervention on negative emotions, pain, and sleep in patients with advanced colon cancer.

作者信息

Wang Gang, Pan Shengjie

机构信息

Department of General Surgery, The First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou City, Jiangsu Province, China.

Department of Neurology, The First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou City, Jiangsu Province, China.

出版信息

Clin Transl Oncol. 2025 Mar 31. doi: 10.1007/s12094-025-03910-4.

Abstract

OBJECTIVE

To investigate the effectiveness of psychological interventions in improving negative emotions, pain, and sleep quality among patients with advanced colon cancer.

METHODS

From March 2021 to March 2023, a total of 218 patients with advanced colon cancer were selected from the First Affiliated Hospital of Soochow University based on strict inclusion and exclusion criteria. Patients were randomly assigned to either the control group or the observation group (109 patients each) using a random number table. The control group received standard medical care, while the observation group received psychological interventions. Both groups were assessed for anxiety and depression levels [using the Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS)], sleep quality [measured by the Pittsburgh Sleep Quality Index (PSQI)], pain intensity [using the Visual Analog Scale (VAS)], and overall quality of life. Inter-group comparisons were conducted.

RESULTS

Post-intervention assessments showed a decrease in SAS and SDS scores for both groups, with the observation group demonstrating a more significant reduction (P < 0.05). Additionally, the observation group reported significantly lower pain levels (VAS scores) and improved sleep quality (PSQI scores) compared to the control group, along with a markedly higher quality of life as measured by the Quality of Life Core Questionnaire (QLQ-30) (P < 0.05).

CONCLUSION

This study demonstrates that psychological interventions effectively alleviate anxiety, depression, pain, and sleep disturbances in patients with advanced colon cancer, thereby improving their overall quality of life. However, further studies are required to explore the long-term impact on prognosis.

摘要

目的

探讨心理干预对改善晚期结肠癌患者负面情绪、疼痛及睡眠质量的有效性。

方法

2021年3月至2023年3月,根据严格的纳入和排除标准,从苏州大学附属第一医院选取218例晚期结肠癌患者。使用随机数字表将患者随机分为对照组和观察组(每组109例)。对照组接受标准医疗护理,观察组接受心理干预。对两组患者的焦虑和抑郁水平[采用焦虑自评量表(SAS)和抑郁自评量表(SDS)]、睡眠质量[采用匹兹堡睡眠质量指数(PSQI)测量]、疼痛强度[采用视觉模拟量表(VAS)]及总体生活质量进行评估,并进行组间比较。

结果

干预后评估显示,两组患者的SAS和SDS评分均有所下降,观察组下降更为显著(P<0.05)。此外,与对照组相比,观察组的疼痛水平(VAS评分)显著降低,睡眠质量(PSQI评分)得到改善,且生活质量核心问卷(QLQ-30)测量的生活质量明显更高(P<0.05)。

结论

本研究表明,心理干预可有效缓解晚期结肠癌患者的焦虑、抑郁、疼痛及睡眠障碍,从而提高其总体生活质量。然而,需要进一步研究以探讨其对预后的长期影响。

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