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澳大利亚新南威尔士州四个社区中LifeSpan自杀预防模式对自我伤害和自杀的影响:一项阶梯式楔形整群随机对照试验。

Effect of the LifeSpan suicide prevention model on self-harm and suicide in four communities in New South Wales, Australia: a stepped-wedge, cluster randomised controlled trial.

作者信息

Shand Fiona, Torok Michelle, Mackinnon Andrew, Burnett Alexander, Sharwood Lisa N, Batterham Philip J, Calear Alison L, Qian Jiahui, Zeritis Stephanie, Sara Grant, Page Andrew, Cutler Henry, Maple Myfanwy, Draper Brian, McGillivray Lauren, Phillips Matthew, Rheinberger Demee, Zbukvic Isabel, Christensen Helen

机构信息

Black Dog Institute, Randwick, New South Wales, Australia.

Black Dog Institute, Randwick, New South Wales, Australia

出版信息

BMJ Ment Health. 2025 Mar 31;28(1):e301429. doi: 10.1136/bmjment-2024-301429.

DOI:10.1136/bmjment-2024-301429
PMID:40164469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11962778/
Abstract

BACKGROUND

There have been few rigorous evaluations of population, multi-strategy, suicide prevention programmes, despite increasing global recognition that such approaches are needed to reduce suicide.

OBJECTIVE

To examine the effects of a multi-strategy suicide prevention model on age-standardised rates of hospital presenting self-harm and suicide after 24 months of implementation.

METHODS

A stepped-wedge cluster randomised trial was conducted in four sites across New South Wales (NSW), Australia, from 2016 to 2020. Sites were randomised to a starting order and implemented the same set of interventions over a 24-month period. Changes in rates of hospital presenting self-harm and suicide deaths were measured using linked administrative health data sets of persons aged 10 or older.

RESULTS

Negative binomial regression models adjusted for linear trends and seasonality showed that LifeSpan was associated with a 13∙8% (incident response rate 0.86; 95% CI 0.79 to 0.94) reduction in hospital-presenting self-harm rates over the intervention period, compared with preintervention. These effects were not observed in the rest of NSW. There were statistically non-significant changes in suicide death rates during the intervention across all sites.

CONCLUSIONS

Locally implementing a multi-strategy suicide prevention model can reduce rates of hospital presentations for self-harm, but longer implementation and evaluation periods may be required to realise the full impacts of interventions for suicide, as a more intractable outcome.

CLINICAL IMPLICATIONS

Our findings can inform policy at all levels of government to invest in actions that may build cross-sectoral capacity in local communities to detect and respond to suicide risk.

摘要

背景

尽管全球越来越认识到需要采取此类方法来减少自杀,但对针对人群的多策略自杀预防计划进行的严格评估却很少。

目的

探讨多策略自杀预防模式在实施24个月后对按年龄标准化的因自我伤害而就医率和自杀率的影响。

方法

2016年至2020年在澳大利亚新南威尔士州(NSW)的四个地点进行了一项逐步楔形整群随机试验。各地点被随机分配开始顺序,并在24个月内实施同一组干预措施。使用10岁及以上人群的关联行政健康数据集来衡量因自我伤害而就医率和自杀死亡率的变化。

结果

针对线性趋势和季节性进行调整的负二项回归模型显示,与干预前相比,在干预期间,“生命跨度”计划与因自我伤害而就医率降低13.8%(事件响应率0.86;95%置信区间0.79至0.94)相关。在新南威尔士州的其他地区未观察到这些效果。在所有地点的干预期间,自杀死亡率有统计学上无显著意义的变化。

结论

在当地实施多策略自杀预防模式可降低因自我伤害而就医的比率,但可能需要更长的实施和评估期才能实现干预对自杀这一更难处理的结果的全面影响。

临床意义

我们的研究结果可为各级政府的政策提供参考,以投资于可能在当地社区建立跨部门能力以发现和应对自杀风险的行动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c7/11962778/616aec5a7fd4/bmjment-28-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c7/11962778/56881a42ee3a/bmjment-28-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c7/11962778/616aec5a7fd4/bmjment-28-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c7/11962778/56881a42ee3a/bmjment-28-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c7/11962778/616aec5a7fd4/bmjment-28-1-g002.jpg

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Research Priorities in Suicide Prevention: Review of Australian Research from 2010⁻2017 Highlights Continued Need for Intervention Research.自杀预防研究重点:2010-2017 年澳大利亚研究综述突出了干预研究的持续需求。
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