Department of Psychiatry, Psychosomatics, and Psychotherapy, Goethe-Universität Frankfurt, Frankfurt, Germany.
Nursing, Midwifery and Allied Health Professions Research Unit, University of Stirling, Stirling, Scotland, United Kingdom.
PLoS One. 2019 Nov 11;14(11):e0224602. doi: 10.1371/journal.pone.0224602. eCollection 2019.
The 'European Alliance Against Depression' community-based intervention approach simultaneously targets depression and suicidal behaviour by a multifaceted community based intervention and has been implemented in more than 115 regions worldwide. The two main aims of the European Union funded project "Optimizing Suicide Prevention Programmes and Their Implementation in Europe" were to optimise this approach and to evaluate its implementation and impact. This paper reports on the primary outcome of the intervention (the number of completed and attempted suicides combined as 'suicidal acts') and on results concerning process evaluation analysis. Interventions were implemented in four European cities in Germany, Hungary, Portugal and Ireland, with matched control sites. The intervention comprised activities with predefined minimal intensity at four levels: training of primary care providers, a public awareness campaign, training of community facilitators, support for patients and their relatives. Changes in frequency of suicidal acts with respect to a one-year baseline in the four intervention regions were compared to those in the four control regions (chi-square tests). The decrease in suicidal acts compared to baseline in the intervention regions (-58 cases, -3.26%) did not differ significantly (χ2 = 0.13; p = 0.72) from the decrease in the control regions (-18 cases, -1.40%). However, intervention effects differed between countries (χ2 = 8.59; p = 0.04), with significant effects on suicidal acts in Portugal (χ2 = 4.82; p = 0.03). The interviews and observations explored local circumstances in each site throughout the study. Hypothesised mechanisms of action for successful implementation were observed and drivers for 'added-value' were identified: local partnership working and 'in-kind' contributions; an approach which valued existing partnership strengths; and synergies operating across intervention levels. It can be assumed that significant events during the implementation phase had a certain impact on the observed outcomes. However, this impact was, of course, not proven.
“欧洲抑郁症联盟”以社区为基础的干预方法通过多方面的社区干预同时针对抑郁症和自杀行为,已在全球 115 多个地区实施。欧盟资助的项目“优化欧洲预防自杀方案及其实施”的两个主要目标是优化这种方法,并评估其实施和影响。本文报告了干预的主要结果(将完成和企图自杀合并为“自杀行为”)以及关于过程评估分析的结果。干预措施在德国、匈牙利、葡萄牙和爱尔兰的四个欧洲城市实施,有匹配的对照点。干预措施包括在四个层次上进行的具有预定义最小强度的活动:初级保健提供者培训、公众意识运动、社区促进者培训、患者及其家属支持。将四个干预地区相对于一年基线的自杀行为频率变化与四个对照地区进行比较(卡方检验)。与基线相比,干预地区的自杀行为减少(-58 例,-3.26%)与对照地区的自杀行为减少(-18 例,-1.40%)没有显著差异(χ2=0.13;p=0.72)。然而,干预效果在各国之间存在差异(χ2=8.59;p=0.04),葡萄牙的自杀行为有显著效果(χ2=4.82;p=0.03)。访谈和观察在整个研究过程中探索了每个地点的当地情况。观察到了成功实施的假设作用机制和“附加值”的驱动因素:当地伙伴关系工作和“实物”贡献;一种重视现有伙伴关系优势的方法;以及在干预层面上运作的协同作用。可以假设,实施阶段的重大事件对观察到的结果产生了一定的影响。但是,这一影响当然没有得到证明。