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采用多层次干预预防自杀行为:一项集群随机对照试验。

Preventing suicidal behaviours with a multilevel intervention: a cluster randomised controlled trial.

机构信息

Suicide and Mental Health Research Group, University of Otago, PO Box 7343, Mein St, Newtown, Wellington, New Zealand.

University of Otago, PO Box 7343, Mein St, Newtown, Wellington, New Zealand.

出版信息

BMC Public Health. 2018 Jan 16;18(1):140. doi: 10.1186/s12889-018-5032-6.

Abstract

BACKGROUND

In the context of the recent surge in community based multilevel interventions for suicide prevention, all of which show promising results, we discuss the implications of the findings of such an intervention designed for and implemented in New Zealand. The multi-level intervention for suicide prevention in New Zealand (MISP-NZ) was a cluster randomised controlled community intervention trial involving eight hospital regions matched into four pairs and randomised to either the intervention or practice as usual (the control). Intervention regions received 25 months of interventions (01 June 2010 to 30 June 2012) including: 1) training in recognition of suicide risk factors; 2) workshops on mental health issues; 3) community based interventions (linking in with community events); and 4) distribution of print material and information on web-based resources.

RESULTS

There was no significant difference between the change in rate of suicidal behaviours (ISH or self-inflicted deaths) in the intervention group compared with the control group (rate ratio = 1.07, 95% CI 0.82, 1.38).

CONCLUSIONS

This study did not provide substantive evidence that the MISP-NZ intervention had an effect on suicidal behaviours raising important questions about the potential effectiveness of the multilevel intervention model for suicide prevention for all countries. Although a range of factors may account for this unanticipated finding, including inadequate study power, differences in design and intervention focus, and country-specific contextual factors, it is possible that the effectiveness of the multilevel intervention model for reducing suicidal behaviours may have been overstated.

TRIAL REGISTRATION

This trial was retrospectively registered on 11 April 2013. ACTRN12613000399796 .

摘要

背景

在最近社区为基础的多层次干预预防自杀的热潮中,所有这些干预措施都显示出了有希望的结果,我们讨论了为新西兰设计和实施的这种干预措施的结果的意义。新西兰预防自杀的多层次干预(MISP-NZ)是一项集群随机对照社区干预试验,涉及 8 个医院区域,分为 4 对,随机分为干预组或常规实践(对照组)。干预区域接受了 25 个月的干预(2010 年 6 月 1 日至 2012 年 6 月 30 日),包括:1)识别自杀风险因素的培训;2)心理健康问题研讨会;3)基于社区的干预措施(与社区活动联系);4)印刷材料和基于网络资源的信息分发。

结果

干预组与对照组之间自杀行为(ISH 或自我伤害死亡)的变化率没有显著差异(率比=1.07,95%CI 0.82,1.38)。

结论

本研究没有提供实质性证据表明 MISP-NZ 干预对自杀行为有影响,这对所有国家预防自杀的多层次干预模式的潜在有效性提出了重要问题。尽管一系列因素可能导致了这一意外发现,包括研究力量不足、设计和干预重点的差异以及特定国家的背景因素,但多层次干预模式减少自杀行为的有效性可能被夸大了。

试验注册

该试验于 2013 年 4 月 11 日进行了回顾性注册。ACTRN12613000399796。

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