• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

印度肌肉减少症共识:流行病学、病因学、临床影响、筛查及治疗方法

An Indian Consensus on Sarcopenia: Epidemiology, Etiology, Clinical Impact, Screening, and Therapeutic Approaches.

作者信息

Kalra Sanjay, Shaikh Irfan A, Shende Sachin, Kapoor Nitin, Unnikrishnan A G, Sharma O P, Tiwaskar Mangesh H, Vora Agam, Verma Suneet Kumar, Kantroo Viny, Mehta Prashant, Lovesley Daphnee, Sivakumar Nandakumar, Kukreja Bharat Bhushan, Kulkarni Kiran, Deora Ankita

机构信息

Department of Endocrinology, Bharti Hospital, Karnal, Haryana, India.

Department of Medical Affairs & Research, Abbott Healthcare Pvt Ltd., Mumbai, Maharashtra, India.

出版信息

Int J Gen Med. 2025 Mar 26;18:1731-1745. doi: 10.2147/IJGM.S510412. eCollection 2025.

DOI:10.2147/IJGM.S510412
PMID:40165836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11955740/
Abstract

The burden of sarcopenia in India continues to be of significant concern. Its diagnosis is challenging due to the lack of standardized cutoffs for assessing muscle strength, quantity, and function among Indians. This consensus aims to identify features of sarcopenia in Indians and provide culturally relevant recommendations for its management. An expert panel from diverse medical specialties across India arrived at a consensus using the modified Delphi method. The panel recommended that a baseline handgrip strength (HGS) cutoff value of <27.5 kg in males and 18.0 kg in females be defined as low muscle strength for the Indian population. All patients with comorbidities should be screened for sarcopenia. In people with sarcopenia, resistance exercise and nutrition with specialized nutrients such as protein, beta-hydroxy-beta-methylbutyrate (HMB), and micronutrients for at least 3 months were recommended as key interventions.

摘要

印度肌肉减少症的负担仍然令人高度关注。由于缺乏评估印度人肌肉力量、数量和功能的标准化临界值,其诊断具有挑战性。本共识旨在确定印度人肌肉减少症的特征,并为其管理提供符合文化背景的建议。来自印度不同医学专业的专家小组采用改良德尔菲法达成了共识。该小组建议,印度男性的基线握力(HGS)临界值<27.5千克、女性<18.0千克应定义为肌肉力量低下。所有合并症患者均应筛查肌肉减少症。对于肌肉减少症患者,建议进行至少3个月的抗阻运动,并摄入蛋白质、β-羟基-β-甲基丁酸(HMB)等特殊营养素和微量营养素,作为关键干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/b838eeebd25a/IJGM-18-1731-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/4587795de836/IJGM-18-1731-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/46f1283b0b0c/IJGM-18-1731-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/7bba5b27065a/IJGM-18-1731-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/2fe1afcd82c5/IJGM-18-1731-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/b838eeebd25a/IJGM-18-1731-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/4587795de836/IJGM-18-1731-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/46f1283b0b0c/IJGM-18-1731-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/7bba5b27065a/IJGM-18-1731-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/2fe1afcd82c5/IJGM-18-1731-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0b/11955740/b838eeebd25a/IJGM-18-1731-g0005.jpg

相似文献

1
An Indian Consensus on Sarcopenia: Epidemiology, Etiology, Clinical Impact, Screening, and Therapeutic Approaches.印度肌肉减少症共识:流行病学、病因学、临床影响、筛查及治疗方法
Int J Gen Med. 2025 Mar 26;18:1731-1745. doi: 10.2147/IJGM.S510412. eCollection 2025.
2
Normative cutoffs of muscle mass, muscle strength, and frailty for healthy Indian population.健康印度人群肌肉量、肌肉力量和虚弱的规范界值。
Indian J Gastroenterol. 2022 Dec;41(6):591-598. doi: 10.1007/s12664-022-01295-8. Epub 2023 Jan 5.
3
The effects of β-hydroxy-β-methylbutyrate supplementation in patients with sarcopenia: A systematic review and meta-analysis.补充β-羟基-β-甲基丁酸对肌肉减少症患者的影响:一项系统评价和荟萃分析。
Maturitas. 2025 Apr;195:108219. doi: 10.1016/j.maturitas.2025.108219. Epub 2025 Feb 20.
4
Effects of Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Older Adults with Sarcopenia: A Randomized, Double-Blind, Placebo-Controlled Study.β-羟-β-甲基丁酸补充剂对肌少症老年人的影响:一项随机、双盲、安慰剂对照研究。
J Nutr Health Aging. 2023;27(5):329-339. doi: 10.1007/s12603-023-1911-1.
5
The effects of β-hydroxy-β-methylbutyrate or HMB-rich nutritional supplements on sarcopenia patients: a systematic review and meta-analysis.β-羟基-β-甲基丁酸酯或富含β-羟基-β-甲基丁酸酯的营养补充剂对肌肉减少症患者的影响:一项系统评价和荟萃分析。
Front Med (Lausanne). 2024 Jul 12;11:1348212. doi: 10.3389/fmed.2024.1348212. eCollection 2024.
6
The Effect of β-hydroxy-β-methylbutyrate (HMB) on Sarcopenia and Functional Frailty in Older Persons: A Systematic Review.β-羟基-β-甲基丁酸(HMB)对老年人肌肉减少症和功能性虚弱的影响:系统评价。
J Nutr Health Aging. 2019;23(2):145-150. doi: 10.1007/s12603-018-1153-y.
7
Diagnostic cut-offs, prevalence, and biochemical predictors of sarcopenia in healthy Indian adults: The Sarcopenia-Chandigarh Urban Bone Epidemiological Study (Sarco-CUBES).健康印度成年人肌少症的诊断截止值、流行率和生化预测因素:肌少症-昌迪加尔城市骨骼流行病学研究(Sarco-CUBES)。
Eur Geriatr Med. 2020 Oct;11(5):725-736. doi: 10.1007/s41999-020-00332-z. Epub 2020 Jun 5.
8
Singapore multidisciplinary consensus recommendations on muscle health in older adults: assessment and multimodal targeted intervention across the continuum of care.新加坡老年人肌肉健康多学科共识建议:贯穿整个护理连续体的评估和多模式靶向干预。
BMC Geriatr. 2021 May 17;21(1):314. doi: 10.1186/s12877-021-02240-8.
9
Supplementation with β-hydroxy-β-methylbutyrate after resistance training in post-acute care patients with sarcopenia: A randomized, double-blind placebo-controlled trial.补充 β-羟基-β-甲基丁酸(HMB)对急性后期伴有肌肉减少症的患者进行抗阻训练的影响:一项随机、双盲、安慰剂对照试验。
Arch Gerontol Geriatr. 2024 Apr;119:105323. doi: 10.1016/j.archger.2023.105323. Epub 2023 Dec 27.
10
The association of aerobic, resistance, and combined exercises with the handgrip strength of middle-aged and elderly Korean adults: a nationwide cross-sectional study.有氧运动、抗阻运动和结合运动与中老年韩国成年人握力的关系:一项全国性横断面研究。
BMC Geriatr. 2022 Aug 16;22(1):676. doi: 10.1186/s12877-022-03293-z.

本文引用的文献

1
Definition and diagnostic criteria of clinical obesity.临床肥胖的定义和诊断标准。
Lancet Diabetes Endocrinol. 2025 Mar;13(3):221-262. doi: 10.1016/S2213-8587(24)00316-4. Epub 2025 Jan 14.
2
Prevalence and factors associated with sarcopenia among urban and rural Indian adults in middle age: A cross-sectional study from Western India.印度城乡中年成年人肌肉减少症的患病率及相关因素:一项来自印度西部的横断面研究。
PLOS Glob Public Health. 2024 Oct 1;4(10):e0003553. doi: 10.1371/journal.pgph.0003553. eCollection 2024.
3
The Evolving Landscape of Sarcopenia in Asia: A Systematic review and meta-analysis following the 2019 Asian working group for sarcopenia (AWGS) diagnostic criteria.
亚洲肌少症的演变现状:基于 2019 年亚洲肌少症工作组(AWGS)诊断标准的系统评价和荟萃分析。
Arch Gerontol Geriatr. 2025 Jan;128:105596. doi: 10.1016/j.archger.2024.105596. Epub 2024 Jul 31.
4
Diagnosing sarcopenia in clinical practice: international guidelines vs. population-specific cutoff criteria.临床实践中肌肉减少症的诊断:国际指南与特定人群的截断标准
Front Med (Lausanne). 2024 Jul 26;11:1405438. doi: 10.3389/fmed.2024.1405438. eCollection 2024.
5
Unraveling the enigma of sarcopenia and sarcopenic obesity in Indian adults with type 2 diabetes - a comparative cross-sectional study.解开印度2型糖尿病成年人肌肉减少症和肌肉减少性肥胖之谜——一项比较性横断面研究。
Clin Diabetes Endocrinol. 2024 Jun 17;10(1):22. doi: 10.1186/s40842-024-00179-4.
6
Obstacles to the Early Diagnosis and Management of Sarcopenia: Current Perspectives.肌肉减少症的早期诊断和管理障碍:当前观点。
Clin Interv Aging. 2024 Feb 20;19:323-332. doi: 10.2147/CIA.S438144. eCollection 2024.
7
The triad of physiological challenges: investigating the intersection of sarcopenia, malnutrition, and malnutrition-sarcopenia syndrome in patients with COPD - a cross-sectional study.生理挑战三联征:探究慢性阻塞性肺疾病患者中肌肉减少症、营养不良和营养不良-肌肉减少症综合征的交集——一项横断面研究
BMC Pulm Med. 2024 Feb 5;24(1):71. doi: 10.1186/s12890-024-02884-3.
8
SARC-F Score: A Quick Bedside Tool to Screen Sarcopenia in Patients With Cirrhosis.SARC-F评分:一种用于筛查肝硬化患者肌肉减少症的快速床边工具。
J Clin Exp Hepatol. 2024 May-Jun;14(3):101318. doi: 10.1016/j.jceh.2023.101318. Epub 2023 Dec 13.
9
A Critical Review of Current Worldwide Definitions of Sarcopenia.肌少症的全球定义:批判性回顾
Calcif Tissue Int. 2024 Jan;114(1):74-81. doi: 10.1007/s00223-023-01163-3. Epub 2023 Dec 3.
10
Validity and reliability of Squegg device in measuring isometric handgrip strength.Squegg 装置测量等长握力的有效性和可靠性。
Eur Rev Med Pharmacol Sci. 2023 Nov;27(21):10247-10254. doi: 10.26355/eurrev_202311_34300.