Dagnaw Gashaw Getaneh, Gessese Abebe Tesfaye, Abey Solomon Lulie, Bitew Abebe Belete, Berrie Kassahun, Dejene Haileyesus
Department of Veterinary Biomedical Science, College of Veterinary Medicine and Animal Sciences, University of Gondar, Gondar, Ethiopia.
Department of Veterinary Pathobiology, College of Veterinary Medicine and Animal Sciences, University of Gondar, Gondar, Ethiopia.
Front Public Health. 2025 Mar 11;13:1538911. doi: 10.3389/fpubh.2025.1538911. eCollection 2025.
The resurgence of the Chikungunya virus has led to public health concerns due to frequent epidemics worldwide. Chikungunya was first detected in Ethiopia in 2016, and it has been identified in various regions. However, the current status of the disease in Ethiopia remains unknown, underscoring the need for updated information.
To provide up-to-date epidemiological data on the status of Chikungunya in Ethiopia.
A systematic review and meta-analysis were conducted using the PubMed, Scopus, and Google Scholar databases in accordance with the PRISMA guidelines, the literature search was conducted from September to October 2024. The search terms used included 'Chikungunya,' 'Chikungunya Virus,' 'Prevalence,' 'Seroprevalence,' 'Risk Factor,' and 'Ethiopia.' The inclusion criteria covered online articles published between 2016 and 2024 in English and published in Ethiopia. The quality assessment involved independent expert evaluations, and publication bias was assessed using Begg's and Egger's tests. The analysis was performed using STATA 17 software.
A total of five articles met the eligibility criteria and were included in the data extraction. The pooled seroprevalence of Chikungunya in Ethiopia was 24.0%. The highest seroprevalence was reported in the Southern Nations, Nationalities, and Peoples' Region (SNNPR), at 43.6%, while the lowest seroprevalence was in Dire Dawa, at approximately 12.0%. Factors such as occupation, education, age, and sex contributed to the variation in seroprevalence of the disease. Subgroup meta-analysis revealed heterogeneity across the types of studies included. No indications of publication bias or small-study effects were found according to Begg's test or Egger's test.
The pooled prevalence of Chikungunya underscores its significance in Ethiopia, necessitating proactive monitoring, active viral disease surveillance, and robust health system enforcement.
基孔肯雅病毒的再次出现引发了全球公共卫生关注，因为其在世界各地频繁引发疫情。基孔肯雅热于2016年首次在埃塞俄比亚被发现，且已在该国多个地区被确认。然而，埃塞俄比亚该疾病的现状仍不明朗，这凸显了获取最新信息的必要性。
提供埃塞俄比亚基孔肯雅热现状的最新流行病学数据。
按照PRISMA指南，使用PubMed、Scopus和谷歌学术数据库进行系统综述和荟萃分析，文献检索于2024年9月至10月进行。使用的检索词包括“基孔肯雅热”“基孔肯雅病毒”“患病率”“血清阳性率”“危险因素”和“埃塞俄比亚”。纳入标准涵盖2016年至2024年期间以英文发表且发表于埃塞俄比亚的在线文章。质量评估由独立专家进行，使用Begg检验和Egger检验评估发表偏倚。分析使用STATA 17软件进行。
共有五篇文章符合纳入标准并被纳入数据提取。埃塞俄比亚基孔肯雅病毒的合并血清阳性率为24.0%。南部各族州（SNNPR）报告的血清阳性率最高，为43.6%，而最低血清阳性率出现在德雷达瓦，约为12.0%。职业、教育程度、年龄和性别等因素导致了该疾病血清阳性率的差异。亚组荟萃分析显示纳入的各类研究存在异质性。根据Begg检验或Egger检验，未发现发表偏倚或小研究效应的迹象。
基孔肯雅热的合并患病率凸显了其在埃塞俄比亚的重要性，需要进行积极监测、开展病毒性疾病主动监测并加强卫生系统建设。
