Hatori Haruka, Udagawa Nobuyuki, Yoshinari Nobuo, Uenishi Kazuhiro, Sugino Noriyuki, Taguchi Akira
Department of Orthodontics, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.
Department of Biochemistry, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.
Cureus. 2025 Feb 26;17(2):e79731. doi: 10.7759/cureus.79731. eCollection 2025 Feb.
Introduction Acquisition of higher peak bone mass in young women may prevent postmenopausal osteoporosis. Many factors, including nutritional intake, influence peak bone mass. The masticatory ability associated with nutritional intake may be lower in young women with malocclusion than in those with normal occlusion. We investigated the difference in bone mineral density (BMD) and nutritional intake between younger women with normal occlusion and malocclusion. Methods This study involved 45 women (mean age, 20.8 years) with normal occlusion and 49 women (mean age, 21.3 years) with malocclusion. Calcaneal BMD was measured by quantitative ultrasound. All participants completed the Food Frequency Questionnaire (FFQ). Differences in BMD, body mass index (BMI), and FFQ-obtained nutrient values between the two groups were analyzed with an independent t-test. Multiple regression analysis was also conducted to assess the association between BMD and nutrient values in both participants with normal occlusion and malocclusion. Results Participants with malocclusion tended to have lower BMD than those with normal occlusion (p = 0.10). The former had significantly higher vitamin A intake and lower sunlight exposure time than the latter. In the malocclusion group, participants with normal BMI had significantly higher BMD than those with both higher and lower BMI (p = 0.009 and p = 0.004, respectively). High vitamin B12 intake was also associated with higher BMD in this group (p = 0.031). Conclusions Malocclusion in young women influenced calcaneal BMD through nutritional intake, sunlight exposure, and BMI. Orthodontic treatment in young women with malocclusion may contribute to obtaining higher peak bone mass.
引言 在年轻女性中获得更高的峰值骨量可能预防绝经后骨质疏松症。许多因素，包括营养摄入，都会影响峰值骨量。与营养摄入相关的咀嚼能力在错牙合年轻女性中可能低于正常牙合的女性。我们研究了正常牙合和错牙合年轻女性之间骨矿物质密度（BMD）和营养摄入的差异。
方法 本研究纳入了45名平均年龄20.8岁的正常牙合女性和49名平均年龄21.3岁的错牙合女性。通过定量超声测量跟骨BMD。所有参与者均完成了食物频率问卷（FFQ）。两组之间BMD、体重指数（BMI）和FFQ获得的营养素值的差异采用独立t检验进行分析。还进行了多元回归分析，以评估正常牙合和错牙合参与者中BMD与营养素值之间的关联。
结果 错牙合参与者的BMD往往低于正常牙合参与者（p = 0.10）。前者的维生素A摄入量显著高于后者，而阳光暴露时间低于后者。在错牙合组中，BMI正常的参与者的BMD显著高于BMI较高和较低的参与者（分别为p = 0.009和p = 0.004）。高维生素B12摄入量在该组中也与较高的BMD相关（p = 0.031）。
结论 年轻女性的错牙合通过营养摄入、阳光暴露和BMI影响跟骨BMD。对错牙合年轻女性进行正畸治疗可能有助于获得更高的峰值骨量。
