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老年人的口腔健康状况与骨折风险的关联。

Associations between oral health status and risk of fractures in elder adults.

机构信息

Department of Orthopedic Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29, Saemunan-Ro, Jongno-Gu, Seoul, 03181, Republic of Korea.

Clinic of Oral Medicine and Orofacial Pain, Institute of Oral Health Science, Ajou University School of Medicine, 164, Worldcup-Ro, Yeongtong-Gu, Suwon, Gyeonggi-Do, 16499, Republic of Korea.

出版信息

Sci Rep. 2023 Jan 24;13(1):1361. doi: 10.1038/s41598-023-28650-9.

Abstract

Oral health condition, bone mineral density, skeletal muscle mass, fall, fracture, and frailty seem to be strongly interconnected. This study aimed to investigate associations between probability of osteoporotic fractures and oral health in the elderly. In total, 2322 Korean subjects from the 2008-2009 Korea National Health and Nutritional Examination Survey aged over 65 years were included. The 10-year probabilities of major and hip fractures were calculated using the Fracture Risk Assessment (FRAX) tool. Data on anthropometry, skeletal bone mineral density, sociodemographic characteristics, physical activity, individual history of fractures and falls, parental history of osteoporosis, number of teeth, metabolic syndrome, the Decayed, Missing, and Filled permanent Teeth index, and Community Periodontal Index (CPI), were collected. Participants were classified into three groups based on FRAX score for major osteoporotic fractures. A multivariate linear regression analysis was conducted to analyze associations between FRAX scores and oral health-related factors, adjusting for confounding factors. BMI, presence of metabolic syndrome, number of teeth, dental patterns, and CPI score showed significant differences among three groups in males and females. Results from multivariate linear regression analysis demonstrated significant relationships between total tooth number and probabilities of fracture in male and female elderly. The interdisciplinary approach for handling osteoporosis and sarcopenia including dentists, physicians is necessary to facilitate a better quality of life in the elderly.

摘要

口腔健康状况、骨矿物质密度、骨骼肌质量、跌倒、骨折和虚弱似乎密切相关。本研究旨在探讨老年人骨质疏松性骨折的发生概率与口腔健康之间的关系。共纳入 2008-2009 年韩国国家健康和营养检查调查中 2322 名年龄在 65 岁以上的韩国受试者。使用骨折风险评估(FRAX)工具计算主要和髋部骨折的 10 年概率。收集了人体测量学、骨骼骨矿物质密度、社会人口统计学特征、身体活动、个体骨折和跌倒史、父母骨质疏松史、牙齿数量、代谢综合征、恒牙龋齿、缺失和填充指数(Decayed, Missing, and Filled permanent Teeth index,DMFT index)和社区牙周指数(Community Periodontal Index,CPI)等数据。根据主要骨质疏松性骨折的 FRAX 评分,将参与者分为三组。采用多元线性回归分析,调整混杂因素后,分析 FRAX 评分与口腔健康相关因素之间的关系。在男性和女性中,BMI、代谢综合征的存在、牙齿数量、牙齿模式和 CPI 评分在三组之间存在显著差异。多元线性回归分析结果表明,男性和女性老年人的总牙齿数量与骨折概率之间存在显著关系。需要牙医、医生等多学科方法来处理骨质疏松症和肌少症,以提高老年人的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad47/9873794/1a5f65ed7398/41598_2023_28650_Fig1_HTML.jpg

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