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肌间隙“抬顶”改良颈椎椎板成形术治疗脊髓型颈椎病的临床及影像学结果:一项至少随访2年的回顾性研究

Clinical and Radiological Outcomes of Intermuscular "Raising Roof" Modified Cervical Laminoplasty for Cervical Spondylotic Myelopathy: A Retrospective Study of at Least 2 Years Follow-Up.

作者信息

Li Xinhang, Wu Haosen, Xu Liran, Tian Xueshi, Han Gengyu, Sun Yu, Pan Shengfa, Zhao Yanbin, Zhou Feifei

机构信息

Department of Orthopaedics, Peking University Third Hospital, Beijing, China.

Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China.

出版信息

Global Spine J. 2025 Apr 1:21925682251333285. doi: 10.1177/21925682251333285.

Abstract

Study designRetrospective study.ObjectivesThe aim of this study was to evaluate the outcomes of a new modified laminoplasty, intermuscular "raising roof" laminoplasty for patients with cervical spondylotic myelopathy.Methods98 patients with cervical spondylotic myelopathy were involved into the study, including 44 patients underwent intermuscular "raising roof" laminoplasty (RL) and 54 patients underwent unilateral muscle-preserve laminoplasty (UL). The data, including sagittal parameters and clinical scale was collected at preoperative stage and final follow-up (at least 2 years) and compared between RL group and UL group. Multivariable liner regressions were preformed to evaluate the relationship between parameters with significant changes at the final follow-up and changes of CL, postoperative NDI and JOA. The cumulative sum (CUSUM) analysis was used for quantitative assessment of RL learning curve. All cases were divided into the learning phase and the proficiency phase according to the peak of CUSUM curve.ResultsNo significant difference was found between RL group and UL group preoperatively. At final follow-up, patients in RL group showed higher JOA scores and recovery rate (RR) but lower NDI scores. For the cervical alignment, the ROM of RL group was greater significantly than UL group, whereas the T1S of RL group was lower than UL group. For the decompression, the RL group had larger CSA of spinal canal than UL group (C4: 278.16 ± 50.40 vs 233.84 ± 42.71, < .001; C5: 279.12 ± 63.88 vs 232.41 ± 48.38, < .001). For the muscle-preserve effect, the CSA of left-side PM in RL group decreased significantly compared to the preoperative stage on C5 level (2.92 ± 0.66 vs 3.16 ± 1.08, < .05), and RL group showed better postoperative symmetry than UL group. The regression results indicated postoperative CSA of right-side PM on C4 level had positive impact on the change of CL (positive value increasing, = .023). And the postoperative symmetry of PM at C4 had positively correlation with postoperative NDI ( = .034). However, the ages of patients showed negative correlation ( = .012) with postoperative JOA. Operation time of learning phase was significantly longer than proficiency phase (166 ± 34.78 vs 120.65 ± 20.36, < .001), and blood loss of learning phase was significantly higher than proficiency phase (251.90 ± 171.27 vs 148.88 ± 82.02, < .001).ConclusionCompared to UL, RL showed similar recovery of neurological functions, but with better improvement of quality of life, cervical mobility and decompression effect at 2-year follow-up. It provides a new treatment approach for degeneration cervical myelopathy.

摘要

研究设计

回顾性研究。

目的

本研究旨在评估一种新的改良椎板成形术,即肌间隙“掀盖式”椎板成形术治疗脊髓型颈椎病患者的疗效。

方法

98例脊髓型颈椎病患者纳入本研究,其中44例行肌间隙“掀盖式”椎板成形术(RL),54例行单侧肌肉保留椎板成形术(UL)。收集术前及末次随访(至少2年)时矢状面参数和临床量表等数据,并在RL组和UL组之间进行比较。进行多变量线性回归以评估末次随访时发生显著变化的参数与颈椎曲度(CL)变化、术后颈功能障碍指数(NDI)和日本骨科学会(JOA)评分之间的关系。采用累积和(CUSUM)分析对RL学习曲线进行定量评估。根据CUSUM曲线峰值将所有病例分为学习阶段和熟练阶段。

结果

术前RL组和UL组之间无显著差异。末次随访时,RL组患者JOA评分和恢复率(RR)较高,但NDI评分较低。对于颈椎排列,RL组的活动度(ROM)显著大于UL组,而RL组的T1倾斜角(T1S)低于UL组。对于减压情况,RL组的椎管横截面积(CSA)大于UL组(C4:278.16±50.40 vs 233.84±42.71,P<0.001;C5:279.12±63.88 vs 232.41±48.38,P<0.001)。对于肌肉保留效果,RL组C5节段左侧颈后肌群(PM)的CSA较术前显著减小(2.92±0.66 vs 3.16±1.08,P<0.05),且RL组术后对称性优于UL组。回归结果表明,术后C4节段右侧PM的CSA对CL变化有正向影响(正值增加,P=0.023)。且C4节段PM的术后对称性与术后NDI呈正相关(P=0.034)。然而,患者年龄与术后JOA呈负相关(P=0.012)。学习阶段的手术时间显著长于熟练阶段(166±34.78 vs 120.65±20.36,P<0.001),学习阶段的失血量显著高于熟练阶段(251.90±171.27 vs 148.88±82.02,P<0.001)。

结论

与UL相比,RL在2年随访时神经功能恢复相似,但生活质量、颈椎活动度和减压效果改善更好。它为退行性脊髓型颈椎病提供了一种新的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca0e/11962932/e6f0cfc854cc/10.1177_21925682251333285-fig1.jpg

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