Agostinelli Stefano, Zefiro Daniele, Garelli Stefania, Cavagnetto Francesca, Gusinu Marco, Bevegni Monica, Blandino Gladys, Fozza Alessandra, Levrero Fabrizio
UO Fisica Sanitaria, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
UO Radioterapia Oncologica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
J Appl Clin Med Phys. 2025 Jun;26(6):e70080. doi: 10.1002/acm2.70080. Epub 2025 Apr 1.
This work introduces BreastWatch, a Varian Eclipse script tool designed to help medical physicists, dosimetrists, and radiation oncologists easily inspect and improve External Beam Breast Treatment (EBBT) plans using automatic evaluation of protocol dose-constraints enhanced by a Community-Based approach.
BreastWatch examines Eclipse EBBT Plans and Plan Sums, automatically testing the plan's DVH against built-in international EBBT protocol (NRG RTOG1005, ICR Fast-Forward, ICR FAST, and EUROPA 1.2) dose-constraints. Results are displayed using traffic lights and an overall BW-SCORE. To overcome protocol dose-constraints limitations, the script can export plan data and dose values in CSV format to build a Community-Based Plan Library. These data are automatically read back in BreastWatch to check plans against the statistical distribution of similar Community plans and compute a CB-SCORE, which complements the protocol-based BW-SCORE. In this paper, BreastWatch v.1.6.5.0 script's design and strengths are examined and discussed, after extensive testing with more than 800 EBBT plans by six experienced planners. In a preliminary analysis, the usefulness of the CB approach is investigated by examining the chronological series of two dose-constraints values (Contra-Lung V3Gy and Heart Average Dose) before and after its introduction in BreastWatch.
We found BreastWatch to speed up the EBBT planning process, while at the same time helping to improve the treatment plans in terms of PTVs coverage and uniformity, sparing of OARs, consistency, and robustness among different planners. The preliminary analysis of the chronological series of two dose-constraints values for a subgroup of 68 EBBT plans shows a trend (p-value = 0.07) for values to be improved and more consistent after the CB approach introduction.
The BreastWatch script is a useful tool for the automatic evaluation of Eclipse EBBT plans. BreastWatch and its Community-Based features have been found to be a simple but effective automation approach to improve the EBBT planning process.
本研究介绍了BreastWatch,这是一种瓦里安Eclipse脚本工具,旨在帮助医学物理学家、剂量师和放射肿瘤学家通过基于社区的方法增强的协议剂量约束自动评估,轻松检查和改进外照射乳腺治疗(EBBT)计划。
BreastWatch检查Eclipse EBBT计划和计划总和,根据内置的国际EBBT协议(NRG RTOG1005、ICR Fast-Forward、ICR FAST和EUROPA 1.2)剂量约束自动测试计划的剂量体积直方图(DVH)。结果通过交通信号灯和总体BW评分显示。为了克服协议剂量约束的局限性,该脚本可以将计划数据和剂量值以CSV格式导出,以构建基于社区的计划库。这些数据会在BreastWatch中自动读回,以根据类似社区计划的统计分布检查计划,并计算补充基于协议的BW评分的CB评分。在本文中,在由六位经验丰富的计划者对800多个EBBT计划进行广泛测试之后,对BreastWatch v.1.6.5.0脚本的设计和优势进行了检查和讨论。在初步分析中,通过检查BreastWatch引入前后两个剂量约束值(对侧肺V3Gy和心脏平均剂量)的时间序列,研究了基于社区方法的有用性。
我们发现BreastWatch加快了EBBT计划制定过程,同时有助于在PTV覆盖范围和均匀性、OARs保护、不同计划者之间的一致性和稳健性方面改进治疗计划。对68个EBBT计划子组的两个剂量约束值的时间序列进行的初步分析显示,在引入基于社区的方法后,值有改善且更一致的趋势(p值 = 0.07)。
BreastWatch脚本是自动评估Eclipse EBBT计划的有用工具。BreastWatch及其基于社区的功能已被证明是一种简单但有效的自动化方法,可改进EBBT计划制定过程。