Calkins Monica E, Jumper Megan, Ered Arielle, Dong Fanghong, Sarpal Deepak K, Baker Krista K, Bencivengo Donna J, Margolis Russell L, Buchanan Robert W, Boumaiz Yasmine, Burris Elizabeth, Campbell Philip D, Chengappa K N Roy, Conroy Catherine, Cooke Akinyi, Dickerson Faith, Flowers Nyasia, Fauble Mandy, Goldberg Richard W, Harvin Alexander, Howell Carolyn, Kelly Christian, Kreyenbuhl Julie, Li Lan, Lucksted Alicia, Marsteller Jill A, Moxam Alexander, Namowicz Denise, Nayar Swati, Oko Jamie, Riggs Jessie, Saravana Arunadevi, Scheinberg Rachel, Smith William R, States Richard, Suhail-Sindhu Timur, Taylor Jerome, Vatza Crystal L, Wolcott Max, Kohler Christian G, Bennett Melanie E
Neurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Early Interv Psychiatry. 2025 Apr;19(4):e70031. doi: 10.1111/eip.70031.
Connection Learning Healthcare System, one of the eight hubs of the National Institute of Mental Health funded Early Psychosis Intervention Network, supports uniform data collection, analysis, feedback and infrastructure development to promote a culture of continuous quality improvement across 25 Coordinated Specialty Care programs serving young people experiencing first episode psychosis and their families in Maryland and Pennsylvania. This first report describes the hub and its constituent programs, the approach for developing and implementing a hub-wide core assessment battery harmonised with the national battery, and preliminary program and participant characteristics.
Our hub developed and implemented a computerised core assessment battery, administered every 6 months and developed an integrated system for managing and analysing data.
Between 1 January 2021 and 27 November 2023, 1059 participants were newly admitted to a hub program. The entire cohort (N = 1381) included newly admitted participants and those already in a program as of 1 January 2021. A total of 1245 complete assessment batteries were collected across all time points from 797 participants, with an additional 1920 partially completed batteries collected from 1319 participants. Data are uploaded to the National Data Coordinating Center, where our hub is the third largest data contributor. Descriptive information on programs and participants is provided.
As part of our learning healthcare system to improve clinical services and outcomes across two states, we have successfully implemented a standardised, computerised core assessment battery of essential characteristics and clinical outcomes. Successes, challenges and recommendations for data collection are provided. This paper will serve as a vital methodological resource for users of the unprecedented Early Psychosis Intervention Network national research database seeking to accelerate and improve early psychosis research.
连接学习医疗系统是美国国立精神卫生研究所资助的早期精神病干预网络的八个中心之一，它支持统一的数据收集、分析、反馈和基础设施建设，以促进25个协调专科护理项目形成持续质量改进的文化氛围，这些项目为马里兰州和宾夕法尼亚州首次发作精神病的年轻人及其家庭提供服务。本首次报告描述了该中心及其组成项目、开发和实施与国家测评工具相协调的全中心核心评估工具的方法，以及项目和参与者的初步特征。
我们的中心开发并实施了一个计算机化的核心评估工具，每6个月进行一次测评，并开发了一个用于管理和分析数据的集成系统。
在2021年1月1日至2023年11月27日期间，有1059名参与者新加入了中心项目。整个队列（N = 1381）包括新加入的参与者以及截至2021年1月1日已参与项目的人员。在所有时间点，共从797名参与者那里收集到1245份完整的评估工具，另外从1319名参与者那里收集到1920份部分完成的评估工具。数据被上传至国家数据协调中心，我们的中心是第三大数据贡献者。文中提供了有关项目和参与者的描述性信息。
作为我们学习医疗系统的一部分，为了改善两个州的临床服务和治疗效果，我们成功实施了一个关于基本特征和临床结果的标准化计算机化核心评估工具。文中提供了数据收集方面的成功经验、挑战及建议。本文将为那些试图加速和改进早期精神病研究的、前所未有的早期精神病干预网络国家研究数据库的用户提供重要的方法学资源。
