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天花板安装的远紫外线灯具可降低有人的临床区域的表面生物负荷。

Ceiling-mounted far-UVC fixtures reduce the surface bioburden in occupied clinical areas.

作者信息

Mogensen Emilie Hage, Jensen Jacob Thyrsted, Skaarup Søren Helbo, Hvass Andreas Fløe, Jeppesen Cecilie Lynggaard, Rasmussen Maja Holst, Røge Birgit Thorup, Joensen Sara Moeslund, Nielsen Stine Yde, Bendstrup Elisabeth, Hauschildt Pernille, Christensen Anne Friesgaard, Holm Christian Kanstrup

机构信息

UV Medico A/S, Aarhus, Denmark.

Department of Biomedicine, Aarhus University, Aarhus, Denmark.

出版信息

Infect Control Hosp Epidemiol. 2025 Apr 3;46(6):1-3. doi: 10.1017/ice.2025.62.

DOI:10.1017/ice.2025.62
PMID:40176386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12169949/
Abstract

Contaminated surfaces in clinics pose a pathogen transmission risk. Far ultraviolet-C light (UVC), with a favorable safety profile for human exposure, has the potential for continuous pathogen inactivation in occupied clinical areas. This study demonstrated real-world bioburden reduction on surfaces, despite frequent contamination from routine use by staff and patients in clinics.

摘要

诊所内被污染的表面会带来病原体传播风险。远紫外线C光（UVC）对人体暴露具有良好的安全性，有可能在有人的临床区域持续灭活病原体。这项研究表明，尽管诊所的工作人员和患者日常频繁使用会造成表面污染，但实际生物负荷仍有所降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f22d/12169949/fad4b3bfdbf2/S0899823X25000625_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f22d/12169949/f5241346b649/S0899823X25000625_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f22d/12169949/fad4b3bfdbf2/S0899823X25000625_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f22d/12169949/f5241346b649/S0899823X25000625_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f22d/12169949/fad4b3bfdbf2/S0899823X25000625_fig2.jpg

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本文引用的文献

1
Evaluation of an automated far ultraviolet-C light technology for decontamination of surfaces and aerosolized viruses in bathrooms.评估一种自动化远紫外 C 光技术对浴室表面和雾化病毒的消毒效果。
Antimicrob Resist Infect Control. 2024 Sep 29;13(1):114. doi: 10.1186/s13756-024-01473-7.
2
Efficacy of a filtered far-UVC handheld disinfection device in reducing the microbial bioburden of hospital surfaces.一种过滤远紫外线手持式消毒设备在降低医院表面微生物生物负荷方面的效果。
Am J Infect Control. 2023 Dec;51(12):1406-1410. doi: 10.1016/j.ajic.2023.05.003. Epub 2023 May 10.
3
Re-Evaluation of Rat Corneal Damage by Short-Wavelength UV Revealed Extremely Less Hazardous Property of Far-UV-C.
远紫外线 C 极弱的危害性：重新评估短波长紫外线对大鼠眼角膜的损伤
Photochem Photobiol. 2021 May;97(3):505-516. doi: 10.1111/php.13419. Epub 2021 May 3.
4
The impact of far-UVC radiation (200-230 nm) on pathogens, cells, skin, and eyes - a collection and analysis of a hundred years of data.远紫外线辐射（200 - 230纳米）对病原体、细胞、皮肤和眼睛的影响——百年数据的收集与分析
GMS Hyg Infect Control. 2021 Feb 16;16:Doc07. doi: 10.3205/dgkh000378. eCollection 2021.
5
Use of Ultraviolet Irradiation in Addition to Commonly Used Hospital Disinfectants or Cleaners Further Reduces the Bioburden on High-Touch Surfaces.除常用的医院消毒剂或清洁剂外，使用紫外线照射可进一步降低高接触表面的生物负荷。
Open Forum Infect Dis. 2019 Dec 17;6(12):ofz529. doi: 10.1093/ofid/ofz529. eCollection 2019 Dec.
6
Germicidal Efficacy and Mammalian Skin Safety of 222-nm UV Light.222纳米紫外线的杀菌效果及对哺乳动物皮肤的安全性
Radiat Res. 2017 Apr;187(4):483-491. doi: 10.1667/RR0010CC.1. Epub 2017 Feb 22.
7
Evidence that contaminated surfaces contribute to the transmission of hospital pathogens and an overview of strategies to address contaminated surfaces in hospital settings.有证据表明，污染的表面会导致医院病原体的传播，本文概述了在医院环境中针对污染表面的处理策略。
Am J Infect Control. 2013 May;41(5 Suppl):S6-11. doi: 10.1016/j.ajic.2012.12.004.
8
Twenty-four-hour observational study of hospital hand hygiene compliance.24 小时观察性研究：医院手卫生依从性。
J Hosp Infect. 2010 Nov;76(3):252-5. doi: 10.1016/j.jhin.2010.06.027. Epub 2010 Sep 20.
9
How long do nosocomial pathogens persist on inanimate surfaces? A systematic review.医院病原体在无生命物体表面能存活多久？一项系统综述。
BMC Infect Dis. 2006 Aug 16;6:130. doi: 10.1186/1471-2334-6-130.
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Guidelines on limits of exposure to ultraviolet radiation of wavelengths between 180 nm and 400 nm (incoherent optical radiation).180纳米至400纳米波长的紫外线辐射（非相干光辐射）暴露限值指南。
Health Phys. 2004 Aug;87(2):171-86. doi: 10.1097/00004032-200408000-00006.