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揭示一名急性肝胆胃肠疾病患者的隐匿性感染

Unmasking an Incidental Infection in a Patient With Acute Hepatobiliary and Gastrointestinal Illness.

作者信息

Chou Yung-Che, Lin Yu-Ta, Er Tze-Kiong

机构信息

Division of Laboratory Medicine, Asia University Hospital Asia University Taichung Taiwan.

Division of Gastroenterology Asia University Hospital Taichung Taiwan.

出版信息

JGH Open. 2025 Apr 2;9(4):e70146. doi: 10.1002/jgh3.70146. eCollection 2025 Apr.

Abstract

BACKGROUND

is a common intestinal parasite, but its systemic impact remains unclear. While severe infections may cause gastrointestinal complications, hepatobiliary involvement is rare. This case describes an incidental infection identified during colonoscopy in a patient hospitalized with acute pancreatitis and suspected gastric outlet obstruction. The study underscores the importance of differentiating incidental parasitic infections from true pathology to prevent misdiagnosis and unnecessary treatment.

CASE PRESENTATION

A 52-year-old female presented with persistent nausea, vomiting, postprandial discomfort, and weight loss for 2 weeks. Imaging revealed hepatomegaly and gastric distension, raising concerns for gastric outlet obstruction or severe gastritis. Laboratory findings showed elevated liver enzymes (ALT: 101 IU/L, Alk-P: 189 IU/L, r-GT: 288 U/L). A viral etiology was suspected but not confirmed. The patient received supportive intravenous therapy, and her symptoms resolved. Colonoscopy revealed a partially clamped adult worm in the transverse colon. Given her clinical improvement without anthelmintic treatment, the infection was deemed incidental and not causative.

CONCLUSION

This case highlights the need to critically evaluate incidental parasitic infections before attributing them to clinical symptoms. Routine screening is valuable but should be accompanied by a thorough assessment of parasite burden, patient history, and clinical presentation to guide appropriate management and prevent unnecessary interventions.

摘要

背景

[寄生虫名称]是一种常见的肠道寄生虫,但其对全身的影响仍不明确。虽然严重感染可能导致胃肠道并发症,但肝胆受累情况罕见。本病例描述了一名因急性胰腺炎住院且疑似胃出口梗阻的患者在结肠镜检查时偶然发现的感染。该研究强调了区分偶然寄生虫感染与真正病理情况以防止误诊和不必要治疗的重要性。

病例介绍

一名52岁女性出现持续恶心、呕吐、餐后不适及体重减轻2周。影像学检查显示肝肿大和胃扩张,引发对胃出口梗阻或严重胃炎的担忧。实验室检查结果显示肝酶升高(谷丙转氨酶:101 IU/L,碱性磷酸酶:189 IU/L,γ-谷氨酰转移酶:288 U/L)。怀疑病毒病因但未得到证实。患者接受了支持性静脉治疗,症状缓解。结肠镜检查发现横结肠内有一条部分夹闭的成虫。鉴于其未经驱虫治疗临床症状改善,该感染被认为是偶然的而非致病原因。

结论

本病例强调在将偶然寄生虫感染归因于临床症状之前需进行严格评估。常规筛查有价值,但应同时对寄生虫负荷、患者病史和临床表现进行全面评估,以指导适当管理并防止不必要的干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a05/11962648/71f16a38de1c/JGH3-9-e70146-g001.jpg

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