Neuronal activities drive brain waste clearance through the glymphatic system.
作者信息
Wang Lin-Jian, Ma Xiwen, Ye Jianping
机构信息
Institute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China.
Tianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.
出版信息
Acta Pharm Sin B. 2025 Feb;15(2):1193-1195. doi: 10.1016/j.apsb.2024.11.005. Epub 2024 Nov 13.
Abstract
摘要
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本文引用的文献
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Cerebrospinal fluid flow extends to peripheral nerves further unifying the nervous system.脑脊液流动延伸至外周神经，进一步统一神经系统。
Sci Adv. 2024 Sep 6;10(36):eadn3259. doi: 10.1126/sciadv.adn3259. Epub 2024 Sep 4.
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Commentary: The central lymphatic drainage in pharmacological, surgical and physical therapies of Alzheimer's disease.评论：阿尔茨海默病药物、手术及物理治疗中的中枢淋巴引流
Acta Pharm Sin B. 2024 Jul;14(7):3291-3293. doi: 10.1016/j.apsb.2024.04.018. Epub 2024 Apr 23.
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Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance.神经元动力学指导脑脊髓液的灌注和大脑清除。
Nature. 2024 Mar;627(8002):157-164. doi: 10.1038/s41586-024-07108-6. Epub 2024 Feb 28.
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Multisensory gamma stimulation promotes glymphatic clearance of amyloid.多觉γ刺激促进淀粉样蛋白的神经胶质淋巴清除。
Nature. 2024 Mar;627(8002):149-156. doi: 10.1038/s41586-024-07132-6. Epub 2024 Feb 28.
5
Glymphatic influx and clearance are accelerated by neurovascular coupling.糖酵解流入和清除通过神经血管耦联加速。
Nat Neurosci. 2023 Jun;26(6):1042-1053. doi: 10.1038/s41593-023-01327-2. Epub 2023 Jun 1.
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The glymphatic hypothesis: the theory and the evidence.糖酵解假说：理论与证据。
Fluids Barriers CNS. 2022 Feb 3;19(1):9. doi: 10.1186/s12987-021-00282-z.
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Deep brain optogenetics without intracranial surgery.无需颅内手术的深部脑光遗传学。
Nat Biotechnol. 2021 Feb;39(2):161-164. doi: 10.1038/s41587-020-0679-9. Epub 2020 Oct 5.
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Impaired glymphatic function and clearance of tau in an Alzheimer's disease model.阿尔茨海默病模型中糖酵解功能障碍和 Tau 清除。
Brain. 2020 Aug 1;143(8):2576-2593. doi: 10.1093/brain/awaa179.
9
Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia.在麻醉状态下的小鼠中，糖质淋流增加与 EEG 德尔塔功率高和心率低相关。
Sci Adv. 2019 Feb 27;5(2):eaav5447. doi: 10.1126/sciadv.aav5447. eCollection 2019 Feb.
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Sleep drives metabolite clearance from the adult brain.睡眠促进成年人大脑代谢产物清除。
Science. 2013 Oct 18;342(6156):373-7. doi: 10.1126/science.1241224.
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