Schulte-Frankenfeld Poul M, Breedvelt Josefien J F, Brouwer Marlies E, van der Spek Nadia, Bosmans Guy, Bockting Claudi L
Department of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Department of Pediatric Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Clin Psychol Eur. 2024 Dec 20;6(4):e13717. doi: 10.32872/cpe.13717. eCollection 2024 Dec.
Suicide is a leading cause of death among adolescents and young adults. While only few evidence-based treatments with limited efficacy are available, family processes have recently been posed as a possible alternative target for intervention. Here, we review the evidence for Attachment-Based Family Therapy (ABFT), a guideline-listed treatment targeting intrafamilial ruptures and building protective caregiver-child relationships.
PubMed, PsycINFO, Embase, and Scopus were searched for prospective trials on ABFT in youth published up until November 6, 2023, and including measures of suicidality. Results were independently screened by two researchers following PRISMA guidelines. Risk of bias was assessed using the Cochrane RoB-2 framework. A random effects meta-analysis was conducted on suicidal ideation and depressive symptoms post-intervention scores in randomized-controlled trials (RCTs).
Seven articles reporting on four RCTs ( = 287) and three open trials ( = 45) were identified. Mean age of participants was = 15.2 years and the majority identified as female (~80%). Overall, ABFT was not significantly more effective in reducing youth suicidal ideation, = 0.40, 95% CI [-0.12, 0.93], nor depressive symptoms, = 0.33, 95% CI [-0.18, 0.84], compared to investigated controls (Waitlist, (Enhanced) Treatment as Usual, Family-Enhanced Nondirective Supportive Therapy).
Evidence is strongly limited, with few available trials, small sample sizes, high sample heterogeneity, attrition rates, and risk of bias. While not generally superior to other treatments, ABFT might still be a clinically valid option in specific cases and should be further investigated. Clinicians are currently recommended to apply caution when considering ABFT as stand-alone intervention for suicidal youth and to decide on a case-by-case basis.
自杀是青少年和青年成年人死亡的主要原因。虽然仅有少数基于证据且疗效有限的治疗方法,但家庭过程最近被视为一种可能的替代干预目标。在此,我们综述了基于依恋的家庭治疗(ABFT)的证据,这是一种列入指南的治疗方法,旨在解决家庭内部的关系破裂问题,并建立具有保护作用的照顾者 - 儿童关系。
检索了PubMed、PsycINFO、Embase和Scopus数据库,查找截至2023年11月6日发表的关于ABFT在青少年中的前瞻性试验,并包括自杀倾向的测量指标。两名研究人员按照PRISMA指南独立筛选结果。使用Cochrane RoB - 2框架评估偏倚风险。对随机对照试验(RCT)中干预后自杀意念和抑郁症状评分进行随机效应荟萃分析。
共识别出7篇文章,报告了4项RCT(n = 287)和3项开放试验(n = 45)。参与者的平均年龄为15.2岁,大多数为女性(约80%)。总体而言,与所研究的对照(等候名单、(强化)常规治疗、家庭强化非指导性支持治疗)相比,ABFT在减少青少年自杀意念(ES = 0.40,95% CI [-0.12, 0.93])和抑郁症状(ES = 0.33,95% CI [-0.18, 0.84])方面并无显著更有效。
证据非常有限,现有试验数量少、样本量小、样本异质性高、失访率高以及存在偏倚风险。虽然ABFT一般并不优于其他治疗方法,但在特定情况下仍可能是一种临床有效的选择,应进一步研究。目前建议临床医生在考虑将ABFT作为自杀青少年的单一干预措施时要谨慎,并应逐案决定。