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用于双相情感障碍初始治疗期间症状监测及向患者和临床医生反馈的MinDag应用程序——一项可行性研究。

The MinDag app for symptom monitoring and feedback to patients and clinicians during the initial treatment of bipolar disorder - a feasibility study.

作者信息

Høegh Margrethe Collier, Glastad Stine Holmstul, Lyngstad Siv Hege, Engen Magnus Johan, Aminoff Sofie Ragnhild, Melle Ingrid, Bjella Thomas, Lagerberg Trine Vik

机构信息

Section for Clinical Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

Nydalen District Psychiatric Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

出版信息

Int J Bipolar Disord. 2025 Apr 3;13(1):14. doi: 10.1186/s40345-025-00382-x.

DOI:10.1186/s40345-025-00382-x
PMID:40178653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11968593/
Abstract

BACKGROUND

The app "MinDag" (MyDay) was developed as a tool for monitoring mood, symptoms and illness-relevant behaviour in the initial treatment of bipolar disorder. Digital self-monitoring may provide patients and clinicians with valuable data for tailoring treatment interventions. This study aims to evaluate the practical use and clinical implications of integrating MinDag in the early treatment of bipolar disorder from the perspectives of both patients and clinicians.

METHODS

The MinDag app includes six content modules covering mood, sleep, functioning/activities, substance use, emotional reactivity, and psychotic symptoms. Patients were asked to use the app for six months, and automated feedback based on the app registrations was delivered to the patients' clinicians biweekly. The study involved quantitative evaluations completed by patients (n = 20), as well as interviews with patients (n = 7) and clinicians (n = 2).

RESULTS

Overall, the patients reported that they felt that MinDag was safe, relevant and easy to use, although technical difficulties such as too many automated reminders and need for reinstallations were reported. The patients appreciated the potential for increased awareness of their mental health, but expressed a desire for direct access to their data. Clinicians found the visual reports and feedback useful for tailoring treatment, even though the alert system for high-risk variables needed refinement. The quantitative evaluations indicated a positive general reception, with suggestions for improvement in usability and accessibility.

CONCLUSION

The MinDag app shows promise as a tool for enhancing the treatment of bipolar disorder by facilitating self-monitoring and providing actionable data to clinicians. However, technical issues and the need for direct patient access to data must be addressed. Development of digital tools to support the treatment of bipolar disorder and other mental health conditions is resource demanding, and there is a need to clarify criteria to establish proof of concept to guide the selection of tools for upscaling and implementation.

摘要

背景

应用程序“MinDag”(我的一天)被开发为一种在双相情感障碍初始治疗中监测情绪、症状和疾病相关行为的工具。数字自我监测可为患者和临床医生提供有价值的数据,以定制治疗干预措施。本研究旨在从患者和临床医生的角度评估将MinDag整合到双相情感障碍早期治疗中的实际用途和临床意义。

方法

MinDag应用程序包括六个内容模块,涵盖情绪、睡眠、功能/活动、物质使用、情绪反应和精神病症状。要求患者使用该应用程序六个月,并每两周将基于应用程序注册的自动反馈发送给患者的临床医生。该研究包括患者(n = 20)完成的定量评估,以及对患者(n = 7)和临床医生(n = 2)的访谈。

结果

总体而言,患者报告称他们觉得MinDag安全、相关且易于使用,不过也报告了一些技术问题,如自动提醒过多和需要重新安装。患者赞赏该应用程序有可能提高他们对自身心理健康的认识,但表示希望能直接获取自己的数据。临床医生发现视觉报告和反馈对定制治疗很有用,尽管高风险变量的警报系统需要改进。定量评估表明总体接受度良好,并提出了在可用性和可及性方面的改进建议。

结论

MinDag应用程序有望成为一种工具,通过促进自我监测并为临床医生提供可操作的数据来加强双相情感障碍的治疗。然而,必须解决技术问题以及患者直接获取数据的需求。开发支持双相情感障碍和其他心理健康状况治疗的数字工具需要大量资源,并且有必要明确建立概念验证的标准,以指导选择用于扩大规模和实施的工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b88/11968593/32873a531ceb/40345_2025_382_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b88/11968593/0f5ba40dd05d/40345_2025_382_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b88/11968593/32873a531ceb/40345_2025_382_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b88/11968593/0f5ba40dd05d/40345_2025_382_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b88/11968593/32873a531ceb/40345_2025_382_Fig2_HTML.jpg

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本文引用的文献

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Digital Tools to Facilitate the Detection and Treatment of Bipolar Disorder: Key Developments and Future Directions.数字工具促进双相情感障碍的检测和治疗:关键进展和未来方向。
JMIR Ment Health. 2024 Apr 1;11:e58631. doi: 10.2196/58631.
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Developing "MinDag" - an app to capture symptom variation and illness mechanisms in bipolar disorder.开发“MinDag”——一款用于捕捉双相情感障碍症状变化和发病机制的应用程序。
Front Med Technol. 2022 Jul 22;4:910533. doi: 10.3389/fmedt.2022.910533. eCollection 2022.
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基于智能手机的双相情感障碍干预措施:疗效的系统评价和荟萃分析。国际双相障碍学会(ISBD)大数据工作组的立场文件。
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