de Dios Eddie, Näslund Olivia, Choudhry Mansor, Berglund Marcus, Skoglund Thomas, Sarovic Darko, Rydén Lina, Kern Silke, Skoog Ingmar, Thurin Erik
Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Department of Radiology, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
Acta Neurochir (Wien). 2025 Apr 3;167(1):98. doi: 10.1007/s00701-025-06506-7.
Meningioma is the most common intracranial primary neoplasm and is often discovered accidentally. Common and non-specific symptoms such as headache and dizziness may be wrongfully attributed to meningiomas, which can lead to unnecessary surgery and anxiety for the patient. Understanding the prevalence of meningioma is therefore pivotal to assess the burden of this disease and determine indications for surgery.
Participants in this study were recruited through "The Gothenburg H70 Birth cohort study" wherein the health of 70-year-olds is examined. Clinical characteristics and symptoms such as sex, body mass index, history of smoking, previous head trauma, previous seizure, headache, dizziness, dementia, and life quality were evaluated. The associations between these variables and the presence of meningioma on MRI were determined.
MRI examinations were collected from 792 participants (415 [52.4%] women) in "The Gothenburg H70 Birth cohort study". The prevalence of meningioma was 1.8% (n = 14). Meningiomas were more common in women (n = 12) than men, but no other significant differences were observed between participants with and without meningiomas.
Meningiomas are common among older women, yet often asymptomatic. Caution should be exercised when attributing symptoms to incidentally discovered small meningiomas, and a conservative approach to treatment may be warranted in these cases.
脑膜瘤是最常见的颅内原发性肿瘤，常为偶然发现。头痛和头晕等常见且非特异性的症状可能被错误地归因于脑膜瘤，这可能导致患者接受不必要的手术并产生焦虑。因此，了解脑膜瘤的患病率对于评估该疾病的负担以及确定手术指征至关重要。
本研究的参与者通过“哥德堡H70出生队列研究”招募，该研究对70岁老人的健康状况进行检查。评估了临床特征和症状，如性别、体重指数、吸烟史、既往头部外伤史、既往癫痫史、头痛、头晕、痴呆和生活质量。确定了这些变量与MRI上脑膜瘤存在之间的关联。
从“哥德堡H70出生队列研究”的792名参与者（415名[52.4%]女性）中收集了MRI检查结果。脑膜瘤的患病率为1.8%（n = 14）。脑膜瘤在女性（n = 12）中比男性更常见，但在有和没有脑膜瘤的参与者之间未观察到其他显著差异。
脑膜瘤在老年女性中很常见，但通常无症状。将症状归因于偶然发现的小脑膜瘤时应谨慎，在这些情况下可能需要采取保守的治疗方法。
