在兔耳中，随着动脉直径减小，乙酰胆碱诱导的内皮依赖性血管舒张增加。
Acetylcholine induced endothelial-dependent vasodilation increases as artery diameter decreases in the rabbit ear.
作者信息
Owen M P, Bevan J A
出版信息
Experientia. 1985 Aug 15;41(8):1057-8. doi: 10.1007/BF01952142.
PMID:4018230
Abstract
Isolated resistance vessels in the rabbit ear preconstricted with histamine were relaxed by acetylcholine by a proportionately greater amount than the central ear artery. The relaxation was antagonized by atropine and also by endothelium removal. Our studies represent the first direct evidence that endothelium-dependent dilation can occur in resistance vessels.
摘要
预先用组胺预收缩的兔耳离体阻力血管，乙酰胆碱使其舒张的程度比中耳动脉更大。阿托品以及去除血管内皮均能拮抗这种舒张作用。我们的研究首次直接证明阻力血管可发生内皮依赖性舒张。
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