Singhal Vinod Kumar, Alaswad Faris Dawood, Senofer Nufra, Ojha Varsha, Md Suleman Adil
General Surgery, Prime Hospital, Dubai, ARE.
Surgery, Gladstone Hospital, Queensland, AUS.
Cureus. 2025 Mar 3;17(3):e80005. doi: 10.7759/cureus.80005. eCollection 2025 Mar.
This study aims to critically evaluate the safety, feasibility, and clinical outcomes of laparoscopic cholecystectomy (LC) in pregnant women.
A retrospective observational study was conducted, reviewing the medical records of 56 pregnant women who underwent LC for gallbladder stones at Prime Hospital, UAE, between January 2015 and December 2023. The inclusion criteria included pregnant women aged 18-42 years who underwent LC for acute or chronic cholecystitis, biliary colic, or in the immediate postpartum period. Exclusion criteria encompassed non-surgical cases and incomplete records. Diagnoses were based on clinical and imaging findings, and all surgeries adhered to a strict protocol to minimize preterm delivery risks. Data on demographics, operative details, and outcomes were analyzed using SPSS (IBM Corp., Armonk, NY).
Among the 56 cases of LC, the participants had a mean age of 32.5 years and an average body mass index (BMI) of 28.4 kg/m², with a mean gestational age of 22.7 weeks. The majority of participants were multiparous (34, 60.7%). Comorbid conditions such as diabetes and hypertension were observed in 12 (21.4%) and 8 (14.3%) cases, respectively. The primary surgical indications included symptomatic cholelithiasis (30, 53.6%) and cholecystitis (20, 35.7%). Intraoperative complications were rare, with minimal bleeding (3, 5.4%) and a low conversion rate to open surgery (2, 3.6%). Postoperative pain was the most common complication (40, 71.4%). Obstetric outcomes included preterm labor (4, 7.1%) and fetal distress (3, 5.4%), though neonatal outcomes were favorable, with high APGAR scores and no fetal deaths reported.
LC in pregnant women is a safe and feasible procedure characterized by low rates of intraoperative and postoperative complications. Postoperative pain was the most frequently observed issue. The majority of deliveries were full-term, with favorable neonatal outcomes. These findings support LC as a viable treatment for gallbladder disease during pregnancy, mainly when performed in the second trimester.
本研究旨在严格评估腹腔镜胆囊切除术（LC）在孕妇中的安全性、可行性及临床结局。
进行了一项回顾性观察研究，回顾了2015年1月至2023年12月期间在阿联酋Prime医院因胆囊结石接受LC手术的56例孕妇的病历。纳入标准包括年龄在18 - 42岁之间，因急性或慢性胆囊炎、胆绞痛或在产后即刻接受LC手术的孕妇。排除标准包括非手术病例和不完整记录。诊断基于临床和影像学检查结果，所有手术均遵循严格方案以尽量降低早产风险。使用SPSS（IBM公司，纽约州阿蒙克）分析人口统计学、手术细节及结局数据。
在56例LC手术病例中，参与者的平均年龄为32.5岁，平均体重指数（BMI）为28.4 kg/m²，平均孕周为22.7周。大多数参与者为经产妇（34例，60.7%）。分别有12例（21.4%）和8例（14.3%）观察到合并症如糖尿病和高血压。主要手术指征包括有症状的胆石症（30例，53.6%）和胆囊炎（20例，35.7%）。术中并发症罕见，少量出血（3例，5.4%）且转为开腹手术的比例较低（2例，3.6%）。术后疼痛是最常见的并发症（40例，71.4%）。产科结局包括早产（4例，7.1%）和胎儿窘迫（3例，5.4%），不过新生儿结局良好，阿氏评分高且无胎儿死亡报告。
孕妇LC手术是一种安全可行的手术，术中及术后并发症发生率低。术后疼痛是最常观察到的问题。大多数分娩为足月产，新生儿结局良好。这些发现支持LC作为孕期胆囊疾病的一种可行治疗方法，主要适用于孕中期进行手术时。
