Rivlin M E, Krueger R P, Wiser W L
Fertil Steril. 1985 Aug;44(2):274-6. doi: 10.1016/s0015-0282(16)48751-0.
Ureteral obstruction caused by endometriosis is uncommon. It is, however, an important complication that imposes a 25% chance for permanent loss of renal function on the affected side. The standard management is surgical; however, three cases have been reported in which regression of obstruction followed medical therapy. This case report concerns a patient with long-standing partial ureteric obstruction due to endometriosis who was treated for 2 months with danazol. Clinical response of the endometriosis was excellent, but the obstruction persisted, a retroperitoneal ureteroneocystotomy was therefore performed. The ureter was found to be obstructed by dense fibrous tissue that contained endometrial glands. It seems therefore that a trial of danazol may be attempted in selected cases, but that the drug is unlikely to relieve endometriotic ureteric obstruction once dense fibrosis has occurred.
子宫内膜异位症引起的输尿管梗阻并不常见。然而，这是一种重要的并发症，会使患侧肾功能永久性丧失的几率达到25%。标准的治疗方法是手术治疗；不过，已有三例报告显示梗阻在药物治疗后消退。本病例报告涉及一名因子宫内膜异位症导致长期部分输尿管梗阻的患者，用达那唑治疗了2个月。子宫内膜异位症的临床反应良好，但梗阻仍然存在，因此进行了腹膜后输尿管膀胱吻合术。发现输尿管被含有子宫内膜腺体的致密纤维组织阻塞。因此，似乎可以在某些特定病例中尝试使用达那唑，但一旦发生致密纤维化，该药物不太可能缓解子宫内膜异位症引起的输尿管梗阻。
