Li Caishan, Wen Licui, Shi Wenyu, Deng Yuqian, Zhou Na, Zhao Xueqing, Hu Ercha, Gailike Bayinchahan
College of Veterinary Medicine, Xinjiang Agricultural University, Xinjiang 830052, China.
Key Laboratory of New Drug Study and Creation for Herbivorous Animals, Xinjiang 830052, China.
J Vet Sci. 2025 Mar;26(2):e19. doi: 10.4142/jvs.24196.
Terpenoids of a plant origin are a class of alternatives to chemical acaricides for tick control. Despite this, few studies have evaluated the efficacy of terpenoid-containing herbal extracts or individual terpenoids in .
This study evaluated the killing efficacy of terpinolene and γ-terpinene against to identify herbs rich in these compounds as potential candidates for future materials in the control of .
Terpinolene and γ-terpinene were subjected to adult tick immersion experiments to evaluate their killing effect on , following their identification post-collection. The herbs were screened for the two terpenoids using the HERB database, and the resulting data were categorized and analyzed.
The acaricidal effect of terpinolene and γ-terpinene against showed a clear dose-response relationship, with effective doses LC₅₀ of 6.60 mg/mL and 4.86 mg/mL, respectively. analysis revealed the presence of terpinolene and γ-terpinene in 52 and 36 herbs, respectively, with 16 herbs containing both compounds. These herbs could be grouped into 35 plant families. In particular, Lamiaceae and Apiaceae emerged as the most represented families, each accounting for 9.23% of the total herbs identified, followed by Zingiberaceae (7.69%) and Asteraceae and Rutaceae (6.15% each).
Terpinolene and γ-terpinolene have good killing effects against . Herbs rich in the two terpenoids are promising candidates as plant-derived materials for managing .
植物源萜类化合物是用于蜱虫防治的化学杀螨剂的一类替代品。尽管如此，很少有研究评估含萜类化合物的草药提取物或单个萜类化合物的功效。
本研究评估了萜品油烯和γ-萜品烯对蜱虫的杀灭效果，以确定富含这些化合物的草药作为未来蜱虫防治材料的潜在候选物。
萜品油烯和γ-萜品烯在采集后经鉴定后，进行成年蜱虫浸泡实验，以评估它们对蜱虫的杀灭效果。使用HERB数据库筛选草药中的这两种萜类化合物，并对所得数据进行分类和分析。
萜品油烯和γ-萜品烯对蜱虫的杀螨效果呈现明显的剂量反应关系，有效剂量LC₅₀分别为6.60毫克/毫升和4.86毫克/毫升。分析显示，分别有52种和36种草药中存在萜品油烯和γ-萜品烯，其中16种草药同时含有这两种化合物。这些草药可分为35个植物科。特别是，唇形科和伞形科是最具代表性的科，各占已鉴定草药总数的9.23%，其次是姜科（7.69%）以及菊科和芸香科（各占6.15%）。
萜品油烯和γ-萜品烯对蜱虫有良好的杀灭效果。富含这两种萜类化合物的草药有望成为用于蜱虫管理的植物源材料。
