吉马大学医学中心收治的心力衰竭患者贫血患病率及相关因素

Prevalence of anemia and associated factors in patients with heart failure admitted to Jimma university medical center.

作者信息

Tegene Elsah, Mohammed Abdulkadir, Godebo Tamirat, Desu Gaddisa, Tadasa Edosa

机构信息

Département of Internal Medicine, Institute of Health, Jimma University, Jimma, Ethiopia.

School of Medical Laboratory Sciences, Faculty of Health Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.

出版信息

BMC Cardiovasc Disord. 2025 Apr 4;25(1):253. doi: 10.1186/s12872-025-04714-8.

DOI:10.1186/s12872-025-04714-8

PMID:40186147

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11969808/

Abstract

BACKGROUND

Anemia is common among adults with heart failure and is linked to increased risks of illness, decreased physical abilities, lower quality of life, more hospital visits, and higher mortality rates. In Ethiopia, about 23% of reproductive-age women and 18% of adult men suffer from anemia. However, data is lacking about its prevalence and associated factors in admitted heart failure patients in our setup.

OBJECTIVES

To determine the prevalence of anemia and associated factors in heart failure patients who were admitted to the emergency and medical ward at Jimma University Medical Center, Southwest Ethiopia.

METHODS

A cross-sectional study was conducted among all heart failure patients admitted to Jimma University Medical Centre from September 1, 2023, to February 30, 2024. A complete blood count was done for these patients. The demographic data and clinical characteristics of study participants were collected using a structured questionnaire. Data was collected on patients' admission and discharge and then data was cleared and entered into a computer using SPSS software version 26. Logistic regression was conducted to declare statistically significant variables with anemia at p-value < 0.05 with 95% CI of Adjusted odds ratio.

RESULTS

A total of 269 participants were involved in the analysis with a mean age of 50.39 ± 18.08 years. The prevalence of anemia among patients with heart failure was 49.8% (43.7-55.9%). Anemia was statistically significant with hypokalaemia: AOR%CI; 3.88(1.6-9.43), creatinine level: AOR%CI; 3.58(1.74-7.38), re-admission: AOR%CI; 3.7(1.63-8.39), and length of hospital stay AOR%CI; 4.11(2.18-7.78).

CONCLUSION

In the current study, nearly half of admitted heart failure patients had anemia, which is associated with hypokalaemia, high creatinine level, readmission, and a longer duration of hospital stay. There was a high prevalence and clinical impact of anemia heart failure patients in our study.

摘要

背景

贫血在成年心力衰竭患者中很常见，并且与患病风险增加、身体能力下降、生活质量降低、更多次住院以及更高的死亡率相关。在埃塞俄比亚，约23%的育龄妇女和18%的成年男性患有贫血。然而，在我们所在地区，关于住院心力衰竭患者中贫血的患病率及其相关因素的数据尚缺。

目的

确定埃塞俄比亚西南部吉马大学医学中心急诊和内科病房收治的心力衰竭患者中贫血的患病率及其相关因素。

方法

对2023年9月1日至2024年2月30日期间收治于吉马大学医学中心的所有心力衰竭患者进行了一项横断面研究。对这些患者进行了全血细胞计数。使用结构化问卷收集研究参与者的人口统计学数据和临床特征。收集患者入院和出院时的数据，然后清理数据并使用SPSS 26版软件录入计算机。进行逻辑回归分析以确定贫血的统计学显著变量，p值<0.05，调整优势比的95%置信区间。

结果

共有269名参与者纳入分析，平均年龄为50.39±18.08岁。心力衰竭患者中贫血的患病率为49.8%（43.7 - 55.9%）。贫血与低钾血症具有统计学显著相关性：调整优势比%置信区间；3.88（1.6 - 9.43），肌酐水平：调整优势比%置信区间；3.58（1.74 - 7.38），再次入院：调整优势比%置信区间；3.7（1.63 - 8.39），以及住院时间调整优势比%置信区间；4.11（2.18 - 7.78）。