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头痛、心脏传导阻滞与心脏肿瘤:恶性黑色素瘤的不寻常表现

Headaches, Heart Block, and a Heart Tumor: Unusual Presentation of Malignant Melanoma.

作者信息

Sohrabian Sahar, Mehrinfar-Zadeh Ramona

机构信息

Cardiology, University of California, Los Angeles, Los Angeles, USA.

出版信息

Cureus. 2025 Mar 7;17(3):e80235. doi: 10.7759/cureus.80235. eCollection 2025 Mar.

Abstract

Cardiac tumors may range from benign primary cardiac masses to malignant metastatic tumors. The constellation of systemic symptoms and presenting findings in metastatic cardiac tumors may be non-specific and may lead to non-cardiac testing before the diagnosis is confirmed with advanced cardiac imaging. We present a case of malignant melanoma with metastatic disease to the heart presenting with headaches, altered mental status, and complete heart block. A detailed history and dermatologic exam should be pursued in any case of cardiac tumor, as metastatic melanoma has a predilection for cardiac involvement. The prognosis remains poor independent of chemotherapy, immunotherapy, and surgical resection, especially with a higher burden of metastatic disease.

摘要

心脏肿瘤的范围可从良性原发性心脏肿块到恶性转移性肿瘤。转移性心脏肿瘤的全身症状和临床表现可能不具有特异性,可能导致在通过先进的心脏成像确诊之前进行非心脏检查。我们报告一例恶性黑色素瘤转移至心脏的病例,患者表现为头痛、精神状态改变和完全性心脏传导阻滞。对于任何心脏肿瘤病例,都应详细询问病史并进行皮肤科检查,因为转移性黑色素瘤易累及心脏。无论化疗、免疫治疗和手术切除情况如何,预后仍然很差,尤其是转移性疾病负担较高时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3644/11972931/3996142772f4/cureus-0017-00000080235-i01.jpg

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