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PET/MRI在检测食管癌和胃癌方面优于PET/CT:一项荟萃分析。

PET/MRI is superior to PET/CT in detecting oesophago and gastric carcinomas: a meta-analysis.

作者信息

Peng Bo, Sun Hui, Hou Jian, Luo Jian-Xing

机构信息

Department of Radiology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.

Department of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.

出版信息

Cancer Imaging. 2025 Apr 7;25(1):50. doi: 10.1186/s40644-025-00871-3.

Abstract

OBJECTIVES

To compare the accuracy rates of the detection and staging of oesophago and gastric carcinomas between PET/MRI and PET/CT.

METHODS

An extensive librarian-led literature search of PubMed, Embase, Web of Science, the Cochrane Central Library, and CNKI was performed and a meta-analysis was done.

RESULTS

Six studies, including 123 participants, were analyzed. PET/MRI had a comparatively high sensitivity in primary lesion detection compared with PET/CT. (RR = 1.14, 95% CI 1.01-1.29, P = 0.036).PET/MRI had no significant statistical differences in all aspects of TNM staging compared with PET/CT.

CONCLUSIONS

This systematic review confirmed the advantage of PET/MRI in detecting oesophago and gastric carcinomas.Compared with PET/CT, it can reduce unnecessary radiation exposure and can be used in relevant patients without contraindications of MRI.

摘要

目的

比较正电子发射断层扫描/磁共振成像(PET/MRI)与正电子发射断层扫描/计算机断层扫描(PET/CT)对食管癌和胃癌的检测及分期准确率。

方法

由图书馆员主导,对PubMed、Embase、科学引文索引(Web of Science)、考克兰系统评价数据库(Cochrane Central Library)和中国知网(CNKI)进行全面的文献检索,并进行荟萃分析。

结果

分析了6项研究,共123名参与者。与PET/CT相比,PET/MRI在原发灶检测方面具有较高的敏感性。(相对危险度(RR)=1.14,95%置信区间(CI)1.01 - 1.29,P = 0.036)。与PET/CT相比,PET/MRI在TNM分期的各个方面均无显著统计学差异。

结论

本系统评价证实了PET/MRI在检测食管癌和胃癌方面的优势。与PET/CT相比,它可以减少不必要的辐射暴露,可用于无MRI禁忌证的相关患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8164/11974111/5a6b4c96cc00/40644_2025_871_Fig1_HTML.jpg

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